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Titolo:
ASTROCYTOMAS OF THE CEREBELLUM - A COMPARATIVE CLINICOPATHOLOGICAL STUDY OF PILOCYTIC AND DIFFUSE ASTROCYTOMAS
Autore:
HAYOSTEK CJ; SHAW EG; SCHEITHAUER B; OFALLON JR; WEILAND TL; SCHOMBERG PJ; KELLY PJ; HU TC;
Indirizzi:
MAYO CLIN & MAYO FDN,DIV RADIAT ONCOL,200 1ST ST SW ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,DIV RADIAT ONCOL,200 1ST ST SW ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,SURG PATHOL SECT ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,CANC CTR STAT UNIT ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,DEPT NEUROL SURG ROCHESTER MN 55905
Titolo Testata:
Cancer
fascicolo: 3, volume: 72, anno: 1993,
pagine: 856 - 869
SICI:
0008-543X(1993)72:3<856:AOTC-A>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
FLOW-CYTOMETRY; CHILDHOOD; CHILDREN; MANAGEMENT; GLIOBLASTOMA; GLIOMAS; RADIOTHERAPY; PROGNOSIS; FEATURES;
Keywords:
CEREBELLAR ASTROCYTOMAS; DIFFUSE ASTROCYTOMAS; PILOCYTIC ASTROCYTOMAS; PROGNOSTIC FACTORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
C.J. Hayostek et al., "ASTROCYTOMAS OF THE CEREBELLUM - A COMPARATIVE CLINICOPATHOLOGICAL STUDY OF PILOCYTIC AND DIFFUSE ASTROCYTOMAS", Cancer, 72(3), 1993, pp. 856-869

Abstract

Background. The majority of patients with astrocytomas of the cerebellum have an excellent prognosis; however, a small percentage of patients continue to do poorly. To clarify the clinical, pathologic, and treatment characteristics that determine prognosis and therapeutic recommendations, a large group of patients with astrocytic tumors of the cerebellum was reviewed and analyzed. Methods. A clinicopathologic analysis was performed of all patients undergoing initial operation for astrocytomas in the cerebellum between 1960 and 1984. Of the 132 patients,105 patients had pilocytic astrocytomas and 27 had diffuse astrocytomas. Results. Multivariate analysis revealed that the division of pilocytic and diffuse histologic type was the most significant prognostic factor influencing survival. The 5-year, 10-year, and 20-year survival rates were 85%, 81%, and 79%, respectively, for patients with pilocytic astrocytomas and 7%, 7%, and 7%, respectively, for patients with diffuse astrocytomas (P < 0.001). Pilocytic astrocytomas occurred in a younger age group and were more commonly cystic and completely resected. Conclusions. Astrocytomas of the cerebellum can be divided into two principal groups, the pilocytic and the diffuse astrocytomas, each of which has distinct clinical, pathologic, and prognostic characteristics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 15:43:05