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Titolo:
PEDIATRIC BILIARY DISEASE
Autore:
STRAUSS RS; WEISSELBERG B; GRAND RJ;
Indirizzi:
TUFTS UNIV NEW ENGLAND MED CTR,BOSTON FLOATING HOSP CHILDREN,DIV PEDIATR GASTROENTEROL & NUTR BOSTON MA 02111
Titolo Testata:
Current opinion in gastroenterology
fascicolo: 5, volume: 9, anno: 1993,
pagine: 841 - 846
SICI:
0267-1379(1993)9:5<841:PBD>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
R.S. Strauss et al., "PEDIATRIC BILIARY DISEASE", Current opinion in gastroenterology, 9(5), 1993, pp. 841-846

Abstract

Biliary disease in infants and children is due to congenital abnormalities such as biliary atresia and choledochal cysts, as well as genetic disorders such as hemoglobinopathies and cystic fibrosis. Several new models for the pathogenesis of extrahepatic biliary atresia and congenital intrahepatic bile duct diseases have been proposed during the past year. Liver transplantation is being increasingly recognized as the ultimate treatment for biliary atresia, even after a successful Kasai operation. Roux-en-Y hepaticojejunostomy is the recommended standardoperation for choledochal cysts, although several modifications have now been introduced (the anatomy of the pancreaticobiliary junction isthought to be important in the incidence of postoperative complications). Infants and children are increasingly recognized as having asymptomatic cholelithiasis, which often resolves with time. Three additional cases of hepatocellular carcinoma associated with arteriohepatic dysplasia (Alagille syndrome) have also been reported, and the authors suggest yearly screening with hepatic ultrasound examinations as well asmonitoring serum a-fetoprotein levels. Ursodeoxycholic acid is a promising new treatment for patients with cystic fibrosis and hepatobiliary disease, and several small clinical trials have been performed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 22:30:18