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Titolo:
EFFECT OF NIFEDIPINE ON CONTRACTIVE MOTIL ITY AND CILIARY ULTRASTRUCTURE OF RABBIT FALLOPIAN-TUBE
Autore:
YANG L; XU YX;
Indirizzi:
XIAN MED UNIV,DEPT PHARMACOL XIAN 710061 PEOPLES R CHINA
Titolo Testata:
Zhongguo yaoli xuebao
fascicolo: 5, volume: 14, anno: 1993,
pagine: 450 -
SICI:
0253-9756(1993)14:5<450:EONOCM>2.0.ZU;2-O
Fonte:
ISI
Lingua:
CHI
Keywords:
NIFEDIPINE; VERAPAMIL; CINNARIZINE; CALCIUM CHANNEL BLOCKERS; FALLOPIAN TUBES; OVUM TRANSPORT; CILIA; MITOCHONDRIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
7
Recensione:
Indirizzi per estratti:
Citazione:
L. Yang e Y.X. Xu, "EFFECT OF NIFEDIPINE ON CONTRACTIVE MOTIL ITY AND CILIARY ULTRASTRUCTURE OF RABBIT FALLOPIAN-TUBE", Zhongguo yaoli xuebao, 14(5), 1993, pp. 450

Abstract

The effects of nifedipine (Nif ) on the motility of isolated isthmus of rabbit Fallopian tube were studied in comparison with those of verapamil (Ver) and cinnarizine (Cin) . Nif (0.01 mumol.L-1), Ver (0.03 mumol-L-1), and Cin (3 mumol.L-1) inhibited the spontaneous contraction,and the contraction caused by norepinephrine (NE). The pD2' values ofNif, Ver, and Cin were 6. 86, 6.13, and 4.43, respectively. Moreover,both Nif and Ver delayed the ovum transport through the Fallopian tube 48 h after iv chorionic gonadotropin (HCG). Nif did not modify the ultrastructure of the ampulla ciliary microtubule, but it influenced the mitochondrial structure and caused an irregular ciliary motion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/11/18 alle ore 04:13:27