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Titolo:
NITRIC-OXIDE IS A MAJOR MEDIATOR IN REACTIVE HYPEREMIA EVOKED BY A BRIEF CORONARY-OCCLUSION IN THE GUINEA-PIG HEART
Autore:
CHLOPICKI S; GRYGLEWSKI RJ;
Indirizzi:
N COPERNICUS UNIV,SCH MED,DEPT PHARMACOL,UL GRZEGORZECKA 16 PL-31531 KRAKOW POLAND
Titolo Testata:
European journal of pharmacology
fascicolo: 1, volume: 241, anno: 1993,
pagine: 117 - 120
SICI:
0014-2999(1993)241:1<117:NIAMMI>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENDOTHELIAL-CELLS; HYPEREMIC RESPONSE; CONSCIOUS DOG; L-ARGININE; RELEASE;
Keywords:
NITRIC OXIDE (NO); REACTIVE HYPEREMIA; HEART (GUINEA PIG);
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
S. Chlopicki e R.J. Gryglewski, "NITRIC-OXIDE IS A MAJOR MEDIATOR IN REACTIVE HYPEREMIA EVOKED BY A BRIEF CORONARY-OCCLUSION IN THE GUINEA-PIG HEART", European journal of pharmacology, 241(1), 1993, pp. 117-120

Abstract

In the isolated perfused guinea pig heart coronary occlusion lasting 1-5 s is followed by reactive hyperaemia which is inhibited by 91-100%after pretreatment with a NO synthase inhibitor, N(G)-nitro-L-arginine (100 muM). Neither indomethacin (5 muM) nor 8-phenyltheophylline (10muM) influences these responses. Therefore, the brief cardiac reactive hyperaemia seems to be predominantly if not entirely mediated by nitric oxide (NO).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 21:29:58