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Titolo:
SNORING AND SLEEP-APNEA IN MEN - ASSOCIATION WITH CENTRAL OBESITY ANDHYPERTENSION
Autore:
GRUNSTEIN R; WILCOX I; YANG TS; GOULD Y; HEDNER J;
Indirizzi:
GOTHENBURG UNIV,SAHLGRENS HOSP,DEPT CLIN PHARMACOL S-41345 GOTHENBURGSWEDEN UNIV SYDNEY,ROYAL PRINCE ALFRED HOSP,CTR SLEEP DISORDERS SYDNEY NSW 2006 AUSTRALIA UNIV SYDNEY,DEPT MED,DAVID READ LAB SYDNEY NSW 2006 AUSTRALIA HORNSBY SLEEP DISORDERS CTR SYDNEY AUSTRALIA
Titolo Testata:
International journal of obesity
fascicolo: 9, volume: 17, anno: 1993,
pagine: 533 - 540
SICI:
0307-0565(1993)17:9<533:SASIM->2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
MUSCLE-FIBER TYPE; BLOOD-PRESSURE; SYSTEMIC HYPERTENSION; APNEA SYNDROME; RISK; DISEASE; THERAPY; FOLLOW; DEATH;
Keywords:
SLEEP APNEA; OBESITY; ABDOMINAL FAT; BLOOD PRESSURE; HYPERTENSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
R. Grunstein et al., "SNORING AND SLEEP-APNEA IN MEN - ASSOCIATION WITH CENTRAL OBESITY ANDHYPERTENSION", International journal of obesity, 17(9), 1993, pp. 533-540

Abstract

The objective of this study was to examine the relationship between sleep apnoea, measures of obesity and blood pressure. The study was cross-sectional in design, involving 1464 consecutive men undergoing sleep studies at two non-hospital sleep laboratories. Detailed sleep studies, body mass index (BMI), neck, hip and waist circumferences and morning and evening blood pressures were measured in each patient. Twenty-eight per cent of patients were obese (BMI > 30 kg/m2) and 47% were overweight (BMI 26-30 kg/m2). Body fat distribution in these patients was typically central with a mean waist-hip ratio (WHR) for the entire group of 0.99 with over 80% of patients having a WHR more than 0.94. Increasing severity of sleep apnoea measured either by respiratory disturbance index (RDI) or minimum oxygen saturation in sleep (MOS) was associated with increasing central obesity and morning but not evening blood pressure. Normal weight patients (BMI < 25 kg/m2) with sleep apnoea were characterized by increased waist and hip circumferences and increased morning diastolic blood pressure compared to patients without sleep apnoea. The best explanatory variables for sleep apnoea were waist (r2 = 0.156, P < 0.001) and age (r2 = 0.013, P = 0.003) only. Morning but not evening blood pressure was related to sleep apnoea independently of obesity and age. We concluded that patients with sleep apnoea are centrally obese. Waist circumference is a better predictor for sleep apnoea than neck circumference or BMI suggesting that the link between obesity and sleep apnoea cannot be explained solely by neck fat deposition. In addition, the degree of sleep apnoea was independently related to morning blood pressure. Sleep apnoea and central obesity are likely to be independent and additive risk factors for increased bloodpressure.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 04:21:41