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Titolo:
TIME-DEPENDENT RHEOLOGICAL BEHAVIOR OF BLOOD AT LOW SHEAR IN NARROW VERTICAL TUBES
Autore:
ALONSO C; PRIES AR; GAEHTGENS P;
Indirizzi:
FREE UNIV BERLIN,INST PHYSIOL,ARNIMALLEE 20 W-1000 BERLIN 33 GERMANY
Titolo Testata:
The American journal of physiology
fascicolo: 2, volume: 265, anno: 1993,
parte:, 2
pagine: 80000553 - 80000561
SICI:
0002-9513(1993)265:2<80000553:TRBOBA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
FLOW-RATES; VISCOSITY; ERYTHROCYTES; AGGREGATION; RESISTANCE;
Keywords:
BLOOD VISCOSITY; RED CELL AGGREGATION; LOW-SHEAR FLOW; MARGINAL PLASMA LAYER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
C. Alonso et al., "TIME-DEPENDENT RHEOLOGICAL BEHAVIOR OF BLOOD AT LOW SHEAR IN NARROW VERTICAL TUBES", The American journal of physiology, 265(2), 1993, pp. 80000553-80000561

Abstract

The time-dependent flow behavior of normal human blood after a suddenreduction of wall shear stress from 5,000 mPa to a low level (2-100 mPa) was studied during perfusion of vertical tubes (internal diam 28-101 mum) at constant driving pressures. Immediately after the implementation of low-shear flow conditions the concentration of red blood cells (RBCs) near the tube wall started to decrease, and marginal plasma spaces developed as a result of the assembly of RBC aggregates. This was associated with a time-dependent increase of flow velocity by up to 200% within 300 s, reflecting a reduction of apparent viscosity. Thesetime-dependent changes of flow behavior increased strongly with decreasing wall shear stress and with increasing tube diameter. A correlation between the width of the marginal plasma layer and relative apparent viscosity was obtained for every condition of tube diameter, wall shear stress, and time. Time-dependent changes of blood rheological properties could be relevant in the circulation, where the blood is exposed to rapid and repeated transitions from high-shear flow conditions inthe arterial and capillary system to low-shear conditions in the venous system.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:41:29