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Titolo:
INTRAEPITHELIAL CORNEAL IMMUNOGLOBULIN CRYSTALS IN IGG-KAPPA MULTIPLE-MYELOMA
Autore:
PERRY HD; DONNENFELD ED; FONT RL;
Indirizzi:
N SHORE UNIV HOSP,LIONS EYE BANK LONG ISL,300 COMMUNITY DR MANHASSET NY 11030
Titolo Testata:
Cornea
fascicolo: 5, volume: 12, anno: 1993,
pagine: 448 - 450
SICI:
0277-3740(1993)12:5<448:ICICII>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Keywords:
DYSPROTEINEMIA; MULTIPLE MYELOMA; MONOCLONAL GAMMOPATHY; IMMUNOGLOBULIN CRYSTALS; IMMUNOHISTOCHEMISTRY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
H.D. Perry et al., "INTRAEPITHELIAL CORNEAL IMMUNOGLOBULIN CRYSTALS IN IGG-KAPPA MULTIPLE-MYELOMA", Cornea, 12(5), 1993, pp. 448-450

Abstract

A 52-year-old man was first examined because of bilateral superficialpunctate keratitis. Slit-lamp examination disclosed numerous intraepithelial minute opacities in both corneas. A corneal biopsy revealed intraepithelial rhomboidal or rectangular crystals that immunohistochemically stained only for IgG-kappa. Serum immunoelectrophoresis demonstrated an IgG-kappa monoclonal gammopathy. Over the ensuing 6 years, theclinical appearance of the crystals changed from small dot-like opacities to polychromatic crystals. At this time, bone marrow examination established the diagnosis of multiple myeloma. Ophthalmologists shouldbe aware of this entity and carefully monitor these patients; the corneal lesions may be the initial manifestation of an asymptomatic monoclonal gammopathy preceding the development of multiple myeloma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 06:35:47