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Titolo:
ANTIPROLIFERATIVE ACTION OF THE STEROID RU486 IN CULTURED HUMAN LYMPHOMA-CELLS
Autore:
SCHUSTER C; CHASSEROTGOLAZ S; BECK G;
Indirizzi:
CNRS,UNITE PROPRE RECH 9002,15 RUE RENE DESCARTES F-67084 STRASBOURG FRANCE CNRS,UNITE PROPRE RECH 9002,15 RUE RENE DESCARTES F-67084 STRASBOURG FRANCE
Titolo Testata:
Cancer letters
fascicolo: 1-3, volume: 71, anno: 1993,
pagine: 43 - 50
SICI:
0304-3835(1993)71:1-3<43:AAOTSR>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
BREAST-CANCER; NUDE-MICE; INHIBITION; RECEPTOR; LINES; TUMORIGENICITY; ANTIPROGESTIN; PROLIFERATION; TOXICITY; HORMONE;
Keywords:
RU486; ANTIPROLIFERATIVE EFFECT; BURKITT LYMPHOMA CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
C. Schuster et al., "ANTIPROLIFERATIVE ACTION OF THE STEROID RU486 IN CULTURED HUMAN LYMPHOMA-CELLS", Cancer letters, 71(1-3), 1993, pp. 43-50

Abstract

The antiproliferative properties of the synthetic steroid RU486 on the human lymphoma cell line Daudi are described. In suspension cultures, RU486 (10 muM) caused a time dose and cell density dependent reduction of cell proliferation. This effect was reversed within 48 h of withdrawal of RU486 from the growth medium. High concentrations of foetal calf serum can mask the inhibitory effect. In semi-solid cultures RU486 also impaired cell proliferation. Thus RU486 was able to suppress inthis tumor cell line the expression of some properties frequently associated with the transformed status of the cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 09:49:47