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Titolo:
EFFECT OF SYSTEMIC-ANAPHYLAXIS ON THE HEPATIC DRUG-METABOLIZING SYSTEM IN RATS
Autore:
ISHIKAWA M; OZAKI M; TAKAYANAGI Y; SASAKI K;
Indirizzi:
TOHOKU COLL PHARMACEUT SCI,CANC RES INST,DEPT PHARMACOL & TOXICOL,4-4-1 KOMATSUSHIMA,AOBA KU SENDAI 981 JAPAN
Titolo Testata:
Japanese Journal of Pharmacology
fascicolo: 4, volume: 62, anno: 1993,
pagine: 407 - 410
SICI:
0021-5198(1993)62:4<407:EOSOTH>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
MICE; INTERFERON; INDUCTION; LIVER;
Keywords:
SYSTEMIC ANAPHYLAXIS (RAT); HEPATIC DRUG-METABOLIZING ACTIVITY;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
M. Ishikawa et al., "EFFECT OF SYSTEMIC-ANAPHYLAXIS ON THE HEPATIC DRUG-METABOLIZING SYSTEM IN RATS", Japanese Journal of Pharmacology, 62(4), 1993, pp. 407-410

Abstract

Rats were immunized by intraperitoneal injection of ovalbumin emulsified with Freund incomplete adjuvant, and then the effect of an intravenous challenge with ovalbumin on hepatic drug-metabolizing enzyme activities was examined. The cytochrome P-450 content and ethylmorphine N-demethylase, benzphetamine N-demethylase, arylhydrocarbon hydroxylase and 7-ethoxycoumarin O-deethylase activities significantly decreased in rats treated with ovalbumin compared with control groups treated with saline, whereas there was no significant reduction in cytochrome b5. NADPH-cytochrome c reductase and NADH-cytochrome c reductase.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/21 alle ore 00:34:59