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Titolo:
SIGNS AND SYMPTOMS IN COMMON COLDS
Autore:
TYRRELL DAJ; COHEN S; SCHLARB JE;
Indirizzi:
PUBL HLTH LAB SERV,CTR APPL MICROBIOL & RES SALISBURY SP4 0JG WILTS ENGLAND HARVARD HOSP,MRC,COMMUN COLD UNIT SALISBURY SP2 8BW WILTS ENGLAND CARNEGIE MELLON UNIV,DEPT PSYCHOL PITTSBURGH PA 15213
Titolo Testata:
Epidemiology and infection
fascicolo: 1, volume: 111, anno: 1993,
pagine: 143 - 156
SICI:
0950-2688(1993)111:1<143:SASICC>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
RHINOVIRUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
D.A.J. Tyrrell et al., "SIGNS AND SYMPTOMS IN COMMON COLDS", Epidemiology and infection, 111(1), 1993, pp. 143-156

Abstract

The patterns of disease caused by five common viruses which infect the respiratory tract are described. The viruses were strains of rhinovirus types 2, 9, and 14, a strain of coronavirus type 229E and of respiratory syncytial virus. Volunteers were given nasal drops containing alow infectious dose of one of the viruses, quarantined from 2 days before to 5 days after inoculation, and examined daily by a clinician using a standard checklist of respiratory signs and symptoms. Only subjects who developed clinical illness accompanied by viral shedding and/or specific antibody production were analysed [n = 116]. The results confirm indication from earlier studies that the main difference betweencolds induced by different viruses is in duration of the incubation period. Patterns of symptom development were not substantially different with different viruses. Analyses of signs and symptoms in different categories, e.g. nasal symptoms v. coughing, justify treatment with different drugs either successively or simultaneously.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/10/20 alle ore 11:04:30