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Titolo:
A COMPARISON OF PERIPHERAL-NERVE REPAIR USING AN ABSORBABLE TUBULIZATION DEVICE AND CONVENTIONAL SUTURE IN PRIMATES
Autore:
TOUNTAS CP; BERGMAN RA; LEWIS TW; STONE HE; PYREK JD; MENDENHALL HV;
Indirizzi:
THREE M CO,BLDG 270-4N-03 ST PAUL MN 55144 HAND SURGEONS MINNESOTA ST PAUL MN 00000 UNIV IOWA,SCH MED IOWA CITY IA 52242 THREE M HLTH CARE ST PAUL MN 00000
Titolo Testata:
Journal of applied biomaterials
fascicolo: 3, volume: 4, anno: 1993,
pagine: 261 - 268
SICI:
1045-4861(1993)4:3<261:ACOPRU>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
LAMININ-CONTAINING GEL; AUTOGENOUS VEIN GRAFT; POLYGLACTIN TUBE; REGENERATION; GUIDES; GAP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
C.P. Tountas et al., "A COMPARISON OF PERIPHERAL-NERVE REPAIR USING AN ABSORBABLE TUBULIZATION DEVICE AND CONVENTIONAL SUTURE IN PRIMATES", Journal of applied biomaterials, 4(3), 1993, pp. 261-268

Abstract

Median nerve regeneration was studied in 30 adult primates after repair by microsurgical suture or tubulization with a nonwoven, bioabsorbable, polyglycolic acid device. The two methods were compared electrophysiologically and histologically 6 and 12 months after repair. The electrophysiology included recording of electrically evoked compound action potentials and subsequent determination of threshold, conduction velocity, amplitude, and area above the baseline for each component. Measurements were obtained before nerve transection and at the time of biopsy by stimulating both proximal and distal to the transection site. Analysis of all electrophysiological parameters revealed no statistically significant differences (p < 0.05) between the two repair techniques. Histopathology included examination of cross sections proximal anddistal to the repair sites and longitudinal sections through the coaptation site. End organs (Meissner's and Pacinian corpuscles and muscle) were sectioned to determine the degree of reinnervation. No significant differences between the repair techniques were observed by histological analysis of these sections. These evaluations indicated that thetubulization repair technique produced results comparable to that of the suture technique. (C) 1993 John Wiley & Sons, Inc.

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Documento generato il 01/12/20 alle ore 10:59:11