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Titolo:
VARIABILITY OF DA DAPI AND C-HETEROCHROMATIC REGIONS - A POPULATION STUDY/
Autore:
TOFANELLI S; STANYON R; AGOSTINI M; FRANCESCHI MG; PAOLI G;
Indirizzi:
UNIV FIRENZE,IST ANTROPOL,VIA PROCONSOLO 12 I-50122 FLORENCE ITALY UNIV GENOA,IST ANTROPOL FIS I-16126 GENOA ITALY UNIV PISA,SEZ ANTROPOL,DIPARTIMENTO SCI COMPORTAMENTO ANIM UOMO I-56100 PISA ITALY
Titolo Testata:
Human biology
fascicolo: 4, volume: 65, anno: 1993,
pagine: 635 - 646
SICI:
0018-7143(1993)65:4<635:VODDAC>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-CHROMOSOMES; ACROCENTRIC CHROMOSOMES; INSITU HYBRIDIZATION; BAND HETEROMORPHISM; SATELLITE DNA; POLYMORPHISM;
Keywords:
CHROMOSOMAL HETEROMORPHISMS; DA/DAPI BANDING; C-BANDING; GARFAGNANA POPULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
S. Tofanelli et al., "VARIABILITY OF DA DAPI AND C-HETEROCHROMATIC REGIONS - A POPULATION STUDY/", Human biology, 65(4), 1993, pp. 635-646

Abstract

DA/DAPI and C chromosomal heteromorphic sites (1q, 9q, 15p, 16q, Yq) in a sample of 136 unrelated individuals from the Garfagnana valley (Tuscany, Italy) have been analyzed quantitatively and qualitatively. The variations in length, between-homolog heteromorphisms, and intensityof fluorescence of the heterochromatic bands have been compared in two subsamples of the population (upper and middle valley) individualized according to geodemographic criteria. DA/DAPI heterochromatin differed significantly from C heterochromatin, showing a lower average amount and a higher variability at each site. This suggests a differential staining of DNA of the two banding systems. Furthermore, DA/DAPI heterochromatin was less uniformly distributed in the population than C heterochromatin and the regions 16q and Yq discriminated better between subsamples. The variations of DA/DAPI fluorescence at the 15p site demonstrated an excess of homomorphic individuals in the upper valley, which could be related to the mating structure of the population living in this area.

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Documento generato il 30/10/20 alle ore 09:35:26