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Titolo:
THE RELATIONSHIP BETWEEN ANKLE BRACHIAL INDEX, OTHER ATHEROSCLEROTIC DISEASE, DIABETES, SMOKING AND MORTALITY IN OLDER MEN AND WOMEN
Autore:
VOGT MT; MCKENNA M; WOLFSON SK; KULLER LH;
Indirizzi:
UNIV PITTSBURGH,GRAD SCH PUBL HLTH,DEPT EPIDEMIOL PITTSBURGH PA 15261 CTR DIS CONTROL,DIV CHRON DIS CONTROL & COMMUNITY INTERVENT ATLANTA GA 30333 UNIV PITTSBURGH,SCH MED,DEPT SURG PITTSBURGH PA 15261
Titolo Testata:
Atherosclerosis
fascicolo: 2, volume: 101, anno: 1993,
pagine: 191 - 202
SICI:
0021-9150(1993)101:2<191:TRBABI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERIPHERAL ARTERIAL-DISEASE; INTERMITTENT CLAUDICATION; FOLLOW-UP; PREVALENCE; MORBIDITY; FRAMINGHAM; RISK; LEG;
Keywords:
AGED; ATHEROSCLEROSIS; MORTALITY; SMOKING; VASCULAR DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
M.T. Vogt et al., "THE RELATIONSHIP BETWEEN ANKLE BRACHIAL INDEX, OTHER ATHEROSCLEROTIC DISEASE, DIABETES, SMOKING AND MORTALITY IN OLDER MEN AND WOMEN", Atherosclerosis, 101(2), 1993, pp. 191-202

Abstract

The goal of this study is to investigate the relationship between peripheral arterial disease and mortality in a large patient population and assess the effects of other atherosclerotic diseases, diabetes and smoking on this relationship. All patients, 50 years or older and withno history of lower extremity surgery, evaluated for lower extremity arterial disease in a university hospital peripheral vascular laboratory over a 13-year period (1977-1989) were included in the study (n = 1930). Arterial disease was assessed by measurement of the resting ankle brachial index (ABI) in these patients. The ABI was calculated by dividing the systolic pressure in the tibial arteries by the pressure inthe brachial artery. Analyses of the data by use of multivariate statistical techniques and by stratification of the patient population by co-morbid condition indicate that ABI is a robust and independent predictor of all-cause mortality in both men (relative risk (RR) = 1.6,95%confidence interval (CI) 1.3,2.0) and women (RR = 1.9,95% CI 1.4, 2.4). The relative risks are essentially unchanged after exclusion of allpatients with clinical history of cardiovascular disease or diabetes. Similarly, a low ABI is an important risk factor for mortality among patients with a history of stroke, angina or diabetes; men and women with a history of smoking and women who are non-smokers. Therefore, themeasurement of ABI, a simple, objective, non-invasive technique whichcan be used in the physician's office, may be useful for early identification of patients at high risk for morbidity and mortality.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 18:31:36