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Titolo:
2-DEOXYGLUCOSE AUTORADIOGRAPHIC EVIDENCE THAT FETAL SUBSTANTIA-NIGRA GRAFTS EXERT CONTRALATERAL EFFECTS IN 6-HYDROXYDOPAMINE-LESIONED ANIMALS WHO RECOVER MOTOR ASYMMETRIES
Autore:
ZAINOSROSALES A; AGUILARROBLERO R; MENDOZARAMIREZ JL; DRUCKERCOLIN R;
Indirizzi:
NATL AUTONOMOUS UNIV MEXICO,INST FISIOL CELULAR,DEPT NEUROCIENCIAS APDO POSTAL 70600 MEXICO CITY 04510 DF MEXICO NATL AUTONOMOUS UNIV MEXICO,INST FISIOL CELULAR,DEPT NEUROCIENCIAS APDO POSTAL 70600 MEXICO CITY 04510 DF MEXICO NATL AUTONOMOUS UNIV MEXICO,FAC MED,DEPT FISIOL MEXICO CITY 04510 DF MEXICO
Titolo Testata:
Neuroscience letters
fascicolo: 1-2, volume: 156, anno: 1993,
pagine: 99 - 104
SICI:
0304-3940(1993)156:1-2<99:2AETFS>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOPAMINE; RAT; METABOLISM; STRIATUM; NUCLEUS;
Keywords:
6-HYDROXYDOPAMINE; SUBSTANTIA-NIGRA; GRAFTING; TURNING BEHAVIOR; 2-DEOXYGLUCOSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
A. Zainosrosales et al., "2-DEOXYGLUCOSE AUTORADIOGRAPHIC EVIDENCE THAT FETAL SUBSTANTIA-NIGRA GRAFTS EXERT CONTRALATERAL EFFECTS IN 6-HYDROXYDOPAMINE-LESIONED ANIMALS WHO RECOVER MOTOR ASYMMETRIES", Neuroscience letters, 156(1-2), 1993, pp. 99-104

Abstract

Fetal substantia nigra grafts decrease turning behavior induced by dopaminergic agonists in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal system. The purpose of this study was to determine, through the [C-14]2-Deoxyglucose autoradiographic method. whether substantia nigra grafts have an effect on efferent striatal nuclei and other related structures. The results showed an unexpected enhancementof metabolic activity in the substantia nigra pars reticulata and striatum on the side contralateral to the lesion and a bilateral enhancement in the thalamus and fronto-parietal cortex, in rats bearing fetal substantia nigra grafts. The results are discussed in terms of the possibility that recovery of turning behavior may in part be caused by anincreased activity of the striatum contralateral to the grafted side.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:22:03