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Titolo:
BREAST-CANCER INCIDENCE AT A NUCLEAR FACILITY - DEMONSTRATION OF A MORBIDITY SURVEILLANCE SYSTEM
Autore:
VAUGHAN TL; LEE JAH; STRADER CH;
Indirizzi:
FRED HUTCHINSON CANC RES CTR,PROGRAM EPIDEMIOL MP-474,1124 COLUMBIA ST SEATTLE WA 98104 HANFORD ENVIRONM HLTH FDN WASHINGTON DC 20545 UNIV WASHINGTON,DEPT EPIDEMIOL SEATTLE WA 98195
Titolo Testata:
Health physics
fascicolo: 4, volume: 64, anno: 1993,
pagine: 349 - 354
SICI:
0017-9078(1993)64:4<349:BIAANF>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOLLOW;
Keywords:
BREAST; CANCER; RADIATION, IONIZING; EXPOSURE, OCCUPATIONAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
T.L. Vaughan et al., "BREAST-CANCER INCIDENCE AT A NUCLEAR FACILITY - DEMONSTRATION OF A MORBIDITY SURVEILLANCE SYSTEM", Health physics, 64(4), 1993, pp. 349-354

Abstract

In order to provide a timely means of identifying new or unexpected toxicities which may occur as a result of occupational exposures, the United States Department of Energy is currently developing a system of routine morbidity surveillance at selected nuclear facilities. Examination of surveillance data at the Hanford Site identified a possible increase in breast cancer incidence (based on three observed cases) among women working in the nuclear trades compared to all other women at the site (relative risk = 3.1; exact 95% confidence interval = 0.7-9.7). This triggered a more detailed investigation using a nested case-control design and individual dosimetry readings. Information on nineteenbreast cancer cases occurring at the site between 1984 and 1989 and 71 matched controls were abstracted from existing occupational medicine, administrative, and health physics records. Summary variables for cumulative, average, and peak external radiation dose equivalents were calculated after allowing for 1 y and 10 y induction and latency periods. There was no evidence that the observed excess was due to radiationexposure. Since the surveillance system is designed to be ongoing, continued monitoring of breast cancer rates in this occupational group will be carried out, and more appropriately detailed studies begun if consistently elevated rates are observed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 18:53:25