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Titolo:
I-123 ALPHA-METHYL TYROSINE SCINTIGRAPHY IN MALIGNANT-MELANOMA
Autore:
STEINERT H; BONI R; HUCHBONI RA; CAPAUL R; VONSCHULTHESS GK; WESTERA G;
Indirizzi:
UNIV ZURICH HOSP,DEPT MED RADIOL,KLIN NUKL MED,RAMISTR 100 CH-8091 ZURICH SWITZERLAND UNIV ZURICH HOSP,DERMATOL KLIN CH-8091 ZURICH SWITZERLAND UNIV ZURICH HOSP,INST DIAGNOST RADIOL CH-8091 ZURICH SWITZERLAND UNIV ZURICH HOSP CH-8091 ZURICH SWITZERLAND
Titolo Testata:
Nuklearmedizin
fascicolo: 2, volume: 36, anno: 1997,
pagine: 36 - 41
Fonte:
ISI
Lingua:
GER
Soggetto:
POSITRON EMISSION TOMOGRAPHY; BRAIN-TUMORS; L-3-)I-123>IODO-ALPHA-METHYL TYROSINE; METASTATIC MELANOMA; SPECT; PET; 2-FLUORINE-18-FLUORO-2-DEOXY-D-GLUCOSE; DERIVATIVES;
Keywords:
MELANOMA; ALPHA-METHYL TYROSINE; I-123 AMT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
H. Steinert et al., "I-123 ALPHA-METHYL TYROSINE SCINTIGRAPHY IN MALIGNANT-MELANOMA", Nuklearmedizin, 36(2), 1997, pp. 36-41

Abstract

Aim: The aim of the study was to evaluate the ranking of the scintigraphy with L-3-I-123-alpha-methyl tyrosine (I-123-AMT) in metastised melanoma. Methods: 26 metastases and one primary tumor of a malignant melanoma in six patients were examined with I-123-AMT whole-body scintigraphy and SPECT. Positron Emission Tomography with 2-F-18-fluoro-2-desoxy-D-glucose (F-18-FDG) was used as the golden standard. Results: With I-123-AMT-SPECT 8/10 metastases in the thorax >1,6 cm were detected (ratio TINT 1,2-1,8), metastases <1,6 cm were not detectable with SPECT. In I-123-AMT whole-body scintigraphy not one lesion showed a positive tumor uptake. Conclusion: In single cases I-123-AMT scintigraphy can be helpful in staging of malignant melanoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 06:19:26