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Titolo:
CHRONIC INGESTION OF ETHANOL INCREASES THE NUMBER OF CA2-NEURONS OF LONG-SLEEP BUT NOT SHORT-SLEEP MICE( CHANNELS OF HIPPOCAMPAL)
Autore:
HUANG GJ; MCARDLE JJ;
Indirizzi:
UMDNJ,NEW JERSEY MED SCH,DEPT PHARMACOL & TOXICOL,185 S ORANGE AVE NEWARK NJ 07103 UMDNJ,NEW JERSEY MED SCH,DEPT PHARMACOL & TOXICOL,185 S ORANGE AVE NEWARK NJ 07103
Titolo Testata:
Brain research
fascicolo: 2, volume: 615, anno: 1993,
pagine: 328 - 330
SICI:
0006-8993(1993)615:2<328:CIOEIT>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
CALCIUM CHANNELS; TOLERANCE; ALCOHOL; DEPENDENCE; CELLS;
Keywords:
ETHANOL; CALCIUM CHANNEL; HIPPOCAMPAL NEURON; SHORT-SLEEP MICE; LONG-SLEEP MICE; TOLERANCE;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
G.J. Huang e J.J. Mcardle, "CHRONIC INGESTION OF ETHANOL INCREASES THE NUMBER OF CA2-NEURONS OF LONG-SLEEP BUT NOT SHORT-SLEEP MICE( CHANNELS OF HIPPOCAMPAL)", Brain research, 615(2), 1993, pp. 328-330

Abstract

Whole cell and single channel Ca2+ currents were compared for hippocampal neurons of normal and ethanol-tolerant long-sleep and short-sleepmice. The properties of these currents were equivalent for normal LS and SS mice. In contrast, the peak amplitude of the whole cell Ca2+ current increased significantly for neurons isolated from LS but not SS mice chronically ingesting ethanol. Since there were no changes in thefunctional properties of single channel events, these data indicate that chronic ingestion of ethanol causes an increase in the number of functional Ca2+ channels in the membrane of hippocampal neurons of LS mice.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 19:05:11