Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
SUBCELLULAR-LOCALIZATION OF IMMUNOREACTIVE OXYTOCIN WITHIN THYMIC EPITHELIAL-CELLS OF THE MALE-MOUSE
Autore:
WIEMANN M; EHRET G;
Indirizzi:
UNIV ULM,VERGLEICHENDE NEUROBIOL ABT,OBERER ESELSBERG M25-5 W-7900 ULM GERMANY
Titolo Testata:
Cell and tissue research
fascicolo: 1, volume: 273, anno: 1993,
pagine: 79 - 87
SICI:
0302-766X(1993)273:1<79:SOIOWT>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURO-ENDOCRINE THYMUS; ARGININE VASOPRESSIN; RAT THYMUS; NEUROHYPOPHYSEAL HORMONES; MONOCLONAL-ANTIBODY; THYMOSIN ALPHA-1; NURSE CELLS; NEUROPHYSIN; PEPTIDES; LYMPHOCYTES;
Keywords:
THYMUS; EPITHELIAL CELLS; OXYTOCIN; IMMUNOCYTOCHEMISTRY; PARACRINE SECRETION; MOUSE (NM-RI);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
M. Wiemann e G. Ehret, "SUBCELLULAR-LOCALIZATION OF IMMUNOREACTIVE OXYTOCIN WITHIN THYMIC EPITHELIAL-CELLS OF THE MALE-MOUSE", Cell and tissue research, 273(1), 1993, pp. 79-87

Abstract

Immunoreactive oxytocin is expressed by thymic epithelial cells, which share properties with neuroendocrine cells. In order to investigate the assumed paracrine secretion of oxytocin, we studied the subcellular localization of immunoreactive oxytocin within thymic tissue and cultured thymic epithelial cells of the male mouse. Three types of immunoreactive cells were distinguished with the electron microscope. Immunoreactive oxytocin was found to be restricted to the cytoplasm by the use of pre- and postembedding methods. Some epithelial cells, especially in the cortex, showed a pronounced labelling of vesicular membranes and membrane tubules of the endoplasmic reticulum. In some cells, keratin filaments were associated with the electron-dense stain. Under culture conditions immunoreactive cells of different shapes were found, all displaying similar patterns of labelling. The contents of differenttypes of vacuoles were only rarely labelled. A special class of immunoreactive exocytotic vesicles could not be identified. Thus, our results do not support neuroendocrine secretion of oxytocin via vesicles ofthymic epithelial cells but offer alternative modes of secretion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 05:04:17