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Titolo:
DOBUTAMINE STRESS-REDISTRIBUTION-REINJECTION VERSUS REST-REDISTRIBUTION TL-201 SPECT IN THE ASSESSMENT OF MYOCARDIAL VIABILITY
Autore:
CORNEL JH; BAX JJ; ELHENDY A; REIJS AEM; FIORETTI PM;
Indirizzi:
MED CTR ALKMAAR,DEPT CARDIOL,WILHELMINALAAN 12 NL-1815 JD ALKMAAR NETHERLANDS UNIV ROTTERDAM,HOSP DIJKZIGT,DEPT NUCL MED ROTTERDAM NETHERLANDS UNIV ROTTERDAM,HOSP DIJKZIGT,THORAXCTR,DIV CARDIOL ROTTERDAM NETHERLANDS UNIV LEIDEN HOSP,DEPT CARDIOL LEIDEN NETHERLANDS
Titolo Testata:
International journal of cardiac imaging
fascicolo: 1, volume: 13, anno: 1997,
pagine: 59 - 64
SICI:
0167-9899(1997)13:1<59:DSVR>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; LEFT-VENTRICULAR FUNCTION; POSITRON EMISSION TOMOGRAPHY; SURGICAL REVASCULARIZATION; COMPUTED-TOMOGRAPHY; TL-201 REINJECTION; METABOLIC-ACTIVITY; VIABLE MYOCARDIUM; PERFUSION; EXERCISE;
Keywords:
MYOCARDIAL VIABILITY; THALLIUM SPECT; DOBUTAMINE-REINJECTION; REST-REDISTRIBUTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
J.H. Cornel et al., "DOBUTAMINE STRESS-REDISTRIBUTION-REINJECTION VERSUS REST-REDISTRIBUTION TL-201 SPECT IN THE ASSESSMENT OF MYOCARDIAL VIABILITY", International journal of cardiac imaging, 13(1), 1997, pp. 59-64

Abstract

The aim of this study was to evaluate the value of thallium-201 chloride (Tl-201) reinjection imaging following dobutamine stress (DRi) to identify viable myocardium in comparison with a rest-redistribution Tl-201 protocol (RR). The identification of viable myocardium bears important consequences for adequate selection of patients with poor left ventricular function, often unable to exercise, who are considered for revascularization. Twenty-six patients with chronic coronary artery disease and depressed left ventricular function (ejection fraction 36 +/- 10%) were studied by both DRi and RR single photon emission computedtomography (SPECT). Semi-quantitative analysis of regional Tl-201 activity (5-point score) and wall motion by echocardiography using a 16-segment model was performed. Regions were classified as viable (normal/reversible/fixed moderate defects) or non-viable (fixed severe defects) and related to regional wall motion. Target heart rate was reached in 25 patients. Myocardial viability was demonstrated in 353/416 (85%) by DRi SPECT and in 346/416 (83%) by RR SPECT. The agreement between the 2 protocols was 98% with a K-value of 0.94; similar results were obtained when the analysis was limited to dyscontractile segments. In conclusion, this study demonstrates the feasibility and diagnostic valueof DRi SPECT to identify viable myocardium.

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Documento generato il 21/01/20 alle ore 01:30:51