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Titolo:
COCULTURES - DIAGNOSTIC AND THERAPEUTIC CONTRIBUTION IN ASSISTED REPRODUCTIVE TECHNOLOGIES
Autore:
JANNY L; VYE P; POULY JL; HAZOUT A; DUMONT M; NICOLLET B; MENEZO Y;
Indirizzi:
HOP HOTEL DIEU,POLICLIN CLERMONT FERRAND,UNITE FIV F-63003 CLERMONT FERRAND FRANCE
Titolo Testata:
Contraception fertilite sexualite
fascicolo: 5, volume: 21, anno: 1993,
pagine: 391 - 394
SICI:
1165-1083(1993)21:5<391:C-DATC>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
FRE
Keywords:
COCULTURE; BLASTOCYST; RANDOMIZED STUDY; FREEZING; REPEATED FAILURES; PATERNAL EFFECTS; EARLY EMBRYO DEVELOPMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
L. Janny et al., "COCULTURES - DIAGNOSTIC AND THERAPEUTIC CONTRIBUTION IN ASSISTED REPRODUCTIVE TECHNOLOGIES", Contraception fertilite sexualite, 21(5), 1993, pp. 391-394

Abstract

Results of french multiple collaborative studies are reported to evaluate the possible benefits of coculture in human IVF program. Prospective randomized study of IVF with transfer on day two versus IVF with transfer on day 6 shows that coculture does not improve overall resultsbut leads to a reduction of triple or quadruple pregnancies. When applied to patients with more than 4 failures of embryo transfers on day 2, delayed transfer of blastocyst results in a hight rate of clinical pregnancy (39 %). Transfers of frozen-thawed blastocysts result in 17,8 % ongoing pregnencies. Coculture is also a powerful tool for understanding early embryo development: when fertilization arises from sperm with poor characteristics or from frozen sperm of donnor, embryo development appears to be altered : in these situations, rate of normaly developing embryo is reduced and early embryo development becomes independent of fertilization rate.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 06:55:07