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Titolo:
ELECTROPHYSIOLOGICAL FEATURES OF HABENULAR NEURONS OF THE GUINEA-PIG - HIGH EFFICACY OF SYNAPTIC TRANSMISSION AND VARIABLE CONFIGURATION OFUNITARY SPIKES
Autore:
YAMAMOTO C; SAWADA S; OHNOSHOSAKU T;
Indirizzi:
KANAZAWA UNIV,FAC MED,DEPT PHYSIOL KANAZAWA ISHIKAWA 920 JAPAN
Titolo Testata:
Neuroscience letters
fascicolo: 1-2, volume: 154, anno: 1993,
pagine: 179 - 182
SICI:
0304-3940(1993)154:1-2<179:EFOHNO>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLINERGIC SYSTEMS; RAT-BRAIN; NUCLEUS;
Keywords:
UNITARY SPIKE; SOMA-DENDRITIC SPIKE; NICOTINIC RECEPTOR; SYNAPTIC TRANSMISSION; HABENULAR NUCLEUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
C. Yamamoto et al., "ELECTROPHYSIOLOGICAL FEATURES OF HABENULAR NEURONS OF THE GUINEA-PIG - HIGH EFFICACY OF SYNAPTIC TRANSMISSION AND VARIABLE CONFIGURATION OFUNITARY SPIKES", Neuroscience letters, 154(1-2), 1993, pp. 179-182

Abstract

Properties of single cell discharges recorded extracellularly in the medial habenular nucleus (MHN) were examined in guinea pig MHN slices. MHN neurons fired spontaneously as well as in response to stimulationof the stria medullaris. Positive deflections representing excitatorypostsynaptic potentials (EPSPs) were recorded in isolation from a neuron. In most neurons, however, EPSPs differentiable from the baseline triggered action potentials consistently, and were recorded in isolation only during administration of 6-cyano-7-nitroquinoxaline-2.3-dione. Increases in spontaneous discharge rate during administration of nicotinic agonists were not accompanied by expected decreases in latency of synaptically-evoked spikes. Action potentials were recorded as biphasic potential changes consisting of a smaller positive phase and a subsequent negative phase. The amplitude of the negative phase in synaptically-evoked spikes fluctuated from trace to trace and was larger thanin spontaneous spikes. The above observations suggest high efficacy of synaptic transmission from the stria medullaris to MHN neurons and variable areas of the soma-dentritic region invaded by action potentials generated in the initial segment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 07:22:56