Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DIAGNOSTIC PITFALLS DURING THERAPY FOR EXTREME HYPERTRIGLYCERIDEMIA
Autore:
ORTH M; LULEY C;
Indirizzi:
UNIV CALIF SAN FRANCISCO,GLADSTONE INST CARDIOVASC DIS,CARDIOVASC RESINST,POB 419100 SAN FRANCISCO CA 94141 UNIV FREIBURG,MED KLIN,KLIN CHEM ABT D-7800 FREIBURG GERMANY
Titolo Testata:
European journal of clinical chemistry and clinical biochemistry
fascicolo: 2, volume: 35, anno: 1997,
pagine: 101 - 103
SICI:
0939-4974(1997)35:2<101:DPDTFE>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIPOPROTEIN-LIPASE GENE; ACUTE-PANCREATITIS; DIABETES-MELLITUS; HYPERLIPIDEMIA; PLASMA; PHENOTYPE; MUTATION; PATIENT; AGAROSE; LIPIDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
M. Orth e C. Luley, "DIAGNOSTIC PITFALLS DURING THERAPY FOR EXTREME HYPERTRIGLYCERIDEMIA", European journal of clinical chemistry and clinical biochemistry, 35(2), 1997, pp. 101-103

Abstract

We report the case of a 34-year-old man with extreme hypertriglyceridaemia (276.6 mmol/l) that was corrected by diet and triple-drug therapy. No primary defect could be found despite an intensive biochemical and genetic evaluation. Early in the time course of triglyceride-lowering therapy, the composition and concentration of different lipoproteinspecies changed markedly. His lipoprotein profile mimicked type III hyperlipidaemia, then familial hypercholesterolaemia, and finally hyperalphalipoproteinaemia. The increase in LDL cholesterol and apolipoprotein B was paralleled by a sixfold increase in lipoprotein(a). We conclude that these different forms of hypercholesterolaemia disappear solely with a continuation of the triglyceride-lowering therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 03:48:20