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Titolo:
SIMULTANEOUS DOBUTAMINE STRESS ECHOCARDIOGRAPHY AND TC-99M ISONITRILESINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY IN PATIENTS WITH SUSPECTEDCORONARY-ARTERY DISEASE
Autore:
FORSTER T; MCNEILL AJ; SALUSTRI A; REIJS AEM; ELSAID EM; ROELANDT JRTC; FIORETTI PM;
Indirizzi:
ERASMUS UNIV ROTTERDAM,DIJKZIGT HOSP,THORAXCTR,DEPT CARDIOL,BA 300,POB 1738 3000 DR ROTTERDAM NETHERLANDS ERASMUS UNIV ROTTERDAM,DIJKZIGT HOSP,THORAXCTR,DEPT CARDIOL,BA 300,POB 1738 3000 DR ROTTERDAM NETHERLANDS ERASMUS UNIV ROTTERDAM,DIJKZIGT HOSP,DEPT NUCL MED 3000 DR ROTTERDAM NETHERLANDS INTERUNIV CARDIOL INST NETHERLANDS ROTTERDAM NETHERLANDS
Titolo Testata:
Journal of the American College of Cardiology
fascicolo: 7, volume: 21, anno: 1993,
pagine: 1591 - 1596
SICI:
0735-1097(1993)21:7<1591:SDSEAT>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR WALL MOTION; EXERCISE ECHOCARDIOGRAPHY; ANGINA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
T. Forster et al., "SIMULTANEOUS DOBUTAMINE STRESS ECHOCARDIOGRAPHY AND TC-99M ISONITRILESINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY IN PATIENTS WITH SUSPECTEDCORONARY-ARTERY DISEASE", Journal of the American College of Cardiology, 21(7), 1993, pp. 1591-1596

Abstract

Objectives. The purpose of this study was to determine the relative value of dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computed tomography (mibi SPECT) in the detection of myocardial ischemia. Background. Stress-induced new wall motion abnormalities and transient perfusion defects are both used for thediagnosis of myocardial ischemia. Methods. One hundred five consecutive patients with either proved or suspected coronary artery disease, who were referred for perfusion scintigraphy, were studied by a combination of the two techniques. Both echocardiographic and mibi SPECT images were visually analyzed. Three patients were excluded from the finalanalysis because of unsatisfactory examinations: two with noninterpretable stress echocardiograms and one with noninterpretable mibi SPECT images. The response to stress was concordantly classified by both techniques in 68% of patients (kappa 0.51). Results. Dobutamine stress echocardiography revealed the presence of ischemia in 38 and mibi SPECT in 45 patients (overall agreement = 74%, kappa = 0.46). The agreement was higher in patients without previous myocardial infarction (84%, kappa = 0.62). When regional analysis was performed, concordance of stress echocardiography and mibi SPECT occurred in 84% of the 306 regions (kappa = 0.45). Regional agreement was also slightly higher in patients without previous infarction (88%, kappa = 0.50). In 21 patients without previous myocardial infarction who underwent coronary angiography,the overall sensitivity of dobutamine stress echocardiography and mibi SPECT for the diagnosis of coronary artery disease (diameter stenosis >50%) was 75% and 83 %, respectively, with a specificity of 89 % (eight of nine patients) for both tests. Conclusions. Dobutamine stress echocardiography represents a reasonable alternative to dobutamine mibiSPECT for the functional assessment of patients with suspected myocardial ischemia and without previous myocardial infarction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 01:07:31