Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE G-CELL
Autore:
SAWADA M; DICKINSON CJ;
Indirizzi:
UNIV MICHIGAN,MED CTR,1500 W MED CTR DR,A510E MSRBI ANN ARBOR MI 48109
Titolo Testata:
Annual review of physiology
, volume: 59, anno: 1997,
pagine: 273 - 298
SICI:
0066-4278(1997)59:<273:TG>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
GASTRIC-ACID SECRETION; GLYCINE-EXTENDED PROGASTRIN; PERFUSED RAT STOMACH; HELICOBACTER-PYLORI INFECTION; VASOACTIVE INTESTINAL POLYPEPTIDE; ZOLLINGER-ELLISON SYNDROME; SOMATOSTATIN SECRETION; COLORECTAL-CARCINOMA; MOLECULAR-CLONING; ALPHA-AMIDATION;
Keywords:
GASTRIN; POSTTRANSLATIONAL PROCESSING; RECEPTORS; HELICOBACTER PYLORI; GROWTH; SIGNAL TRANSDUCTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
147
Recensione:
Indirizzi per estratti:
Citazione:
M. Sawada e C.J. Dickinson, "THE G-CELL", Annual review of physiology, 59, 1997, pp. 273-298

Abstract

The study of gastrin continues to serve as an excellent model for gastrointestinal regulatory processes. This review highlights some recentadvances in the field by outlining gastrin biosynthesis, summarizing current understanding of gastrin receptors, describing the regulation of gastrin release, and discussing the clinical implications of gastrin in the pathogenesis of peptic ulcer disease. Emphasis is on three emerging areas of gastrin research: the novel finding that one of gastrin's posttranslational processing intermediates has biological activitydistinct from that of the mature peptide; elucidation of gastrin's signal transduction mechanisms that mediate the trophic effects of the peptide; and the role of gastrin in peptic ulcer disease pathogenesis secondary to Helicobacter pylori infection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 21:00:11