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Titolo:
INTERNATIONAL COOPERATIVE ATAXIA RATING-SCALE FOR PHARMACOLOGICAL ASSESSMENT OF THE CEREBELLAR SYNDROME
Autore:
TROUILLAS P; TAKAYANAGI T; HALLETT M; CURRIER RD; SUBRAMONY SH; WESSEL K; BRYER A; DIENER HC; MASSAQUOI S; GOMEZ CM; COUTINHO P; BENHAMIDA M; CAMPANELLA G; FILLA A; SCHUT L; TIMANN D; HONNORAT J; NIGHOGHOSSIAN N; MANYAM B;
Indirizzi:
HOP NEUROL,ATAXIA RES CTR,59 BLVD PINEL F-69003 LYON FRANCE HOP NEUROL,ATAXIA RES CTR F-69003 LYON FRANCE HOP NEUROL,CEREBROVASC UNIT F-69003 LYON FRANCE UNIV LYON 1 F-69003 LYON FRANCE NARA MED UNIV,DEPT NEUROL NARA JAPAN NINCDS,NIH BETHESDA MD 20892 UNIV MISSISSIPPI,SCH MED,DEPT NEUROL JACKSON MI 00000 UNIV LUBECK,NEUROL CLIN D-2400 LUBECK GERMANY GROOTE SCHUUR HOSP,NEUROL UNIT ZA-7925 CAPE TOWN SOUTH AFRICA UNIV ESSEN GESAMTHSCH,NEUROL CLIN ESSEN GERMANY UNIV MINNESOTA,ATAXIA CTR MINNEAPOLIS MN 55455 SANTO ANTONIO HOSP,NEUROL SERV OPORTO PORTUGAL HOP RABTA,NATL NEUROL CTR TUNIS TUNISIA UNIV NAPLES FEDERICO II,NEUROL CLIN NAPLES ITALY UNITED HOSP,PAIN CTR ST PAUL MN 00000 SO ILLINOIS UNIV,SCH MED,DEPT NEUROL SPRINGFIELD IL 00000
Titolo Testata:
Journal of the neurological sciences
fascicolo: 2, volume: 145, anno: 1997,
pagine: 205 - 211
SICI:
0022-510X(1997)145:2<205:ICARFP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
OCULAR REFLEX; ANTERIOR LOBE; EYE-MOVEMENTS; DOUBLE-BLIND; ATROPHY; 5-HYDROXYTRYPTOPHAN; IMPROVEMENT; NYSTAGMUS; TRIAL;
Keywords:
CEREBELLAR ATAXIA; RATING SCALE; CONTROLLED DOUBLE-BLIND DRUG PLACEBO STUDIES; COOPERATIVE INTERNATIONAL TRIALS; WORLD FEDERATION OF NEUROLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
P. Trouillas et al., "INTERNATIONAL COOPERATIVE ATAXIA RATING-SCALE FOR PHARMACOLOGICAL ASSESSMENT OF THE CEREBELLAR SYNDROME", Journal of the neurological sciences, 145(2), 1997, pp. 205-211

Abstract

Despite the involvement of cerebellar ataxia in a large variety of conditions and its frequent association with other neurological symptoms, the quantification of the specific core of the cerebellar syndrome is possible and useful in Neurology, Recent studies have shown that cerebellar ataxia might be sensitive to various types of pharmacological agents, but the scales used for assessment were all different. With the long-term goal of double-blind controlled trials-multicentric and international-an ad hoc Committee of the World Federation of Neurology has worked to propose a one-hundred-point semi-quantitative International Cooperative Ataxia Rating Scale (ICARS), The scale proposed involves a compartimentalized quantification of postural and stance disorders, limb ataxia, dysarthria and oculomotor disorders, in order that a subscore concerning these symptoms may be separately studied, The weightof each symptomatologic compartment has been carefully designed, The members of the Committee agreed upon precise definitions of the tests,to minimize interobserver variations. The validation of this scale isin progress. (C) 1997 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:38:47