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Titolo:
INCREASED CONCENTRATION OF ENDOTHELIN MESSENGER-RNA IN THE MESENTERIC-ARTERIES OF CYCLOSPORINE-INDUCED HYPERTENSIVE RATS
Autore:
TAKEDA Y; MIYAMORI I; YONEDA T; TAKEDA R;
Indirizzi:
KANAZAWA UNIV,SCH MED,DEPT INTERNAL MED 2,TAKARA MACHI 13-1 KANAZAWA ISHIKAWA 920 JAPAN
Titolo Testata:
American journal of hypertension
fascicolo: 5, volume: 6, anno: 1993,
parte:, 1
pagine: 427 - 430
SICI:
0895-7061(1993)6:5<427:ICOEMI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Keywords:
ENDOTHELIN-1; MESSENGER RNA; CYCLOSPORINE; HYPERTENSION; WISTAR RAT;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
Y. Takeda et al., "INCREASED CONCENTRATION OF ENDOTHELIN MESSENGER-RNA IN THE MESENTERIC-ARTERIES OF CYCLOSPORINE-INDUCED HYPERTENSIVE RATS", American journal of hypertension, 6(5), 1993, pp. 427-430

Abstract

The aim of this study was to investigate the expression of endothelin-1 (ET-1) in the mesenteric arteries of cyclosporine-induced hypertensive rats. The concentration of plasma ET-1 and of mesenteric artery ET-1 messenger RNA was measured in cyclosporine-induced hypertensive andcontrol rats. The concentration of ET-1 messenger RNA in the mesenteric arteries of cyclosporine-treated rats (25 mg/kg/day for 6 weeks) was significantly greater than in control rats (P < .05). We propose that cyclosporine-induced hypertension may be due to an increased synthesis of ET-1 in the resistant vessels.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:28:47