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Titolo:
ASSOCIATION BETWEEN PREGNANCY-INDUCED HYPERTENSION AND ASTHMA DURING PREGNANCY
Autore:
LEHRER S; STONE J; LAPINSKI R; LOCKWOOD CJ; SCHACHTER BS; BERKOWITZ R; BERKOWITZ GS;
Indirizzi:
MT SINAI MED CTR,DEPT RADIAT ONCOL,BOX 1236 NEW YORK NY 10029 MT SINAI MED CTR,DEPT REPROD SCI NEW YORK NY 10029 MT SINAI MED CTR,DEPT OBSTET GYNECOL NEW YORK NY 10029
Titolo Testata:
American journal of obstetrics and gynecology
fascicolo: 5, volume: 168, anno: 1993,
pagine: 1463 - 1466
SICI:
0002-9378(1993)168:5<1463:ABPHAA>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
GESTATIONAL HYPERTENSION; REMOTE PROGNOSIS; PREECLAMPSIA; WOMEN; RISK;
Keywords:
PREGNANCY-INDUCED HYPERTENSION; ASTHMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
S. Lehrer et al., "ASSOCIATION BETWEEN PREGNANCY-INDUCED HYPERTENSION AND ASTHMA DURING PREGNANCY", American journal of obstetrics and gynecology, 168(5), 1993, pp. 1463-1466

Abstract

OBJECTIVE: Pregnancy-induced hypertension is an important cause of maternal mortality, intrauterine growth retardation, and perinatal mortality. We examined the relationship between pregnancy-induced hypertension and asthma. STUDY DESIGN: The study population consisted of 24,115women without a history of chronic systemic hypertension who were delivered of live born and stillborn infants at Mount Sinai Medical Center between January 1987 and December 1991. Pregnancy-induced hypertension was defined as blood pressure of at least 140/90 mm Hg or an increase of greater-than-or-equal-to 30 mm Hg in systolic pressure or greater-than-or-equal-to 15 mm Hg in diastolic pressure. RESULTS: There was a significant association between pregnancy-induced hypertension and asthma during pregnancy (chi2 = 17.86, p < 0.001). In addition, there was a significant upward trend in the incidence of asthma during pregnancy in women without, with moderate, and with severe pregnancy-inducedhypertension (Mantel-Haenszel chi2 = 11.8, p = 0.001). Logistic regression analysis demonstrated that the association between pregnancy-induced hypertension and asthma during pregnancy persisted after adjustment for the confounding factors of race or ethnicity, maternal age, parity, and prepregnancy weight (adjusted odds ratio 2.52, 95% confidenceinterval 1.47 to 4.35, p = 0.0008). An association between pregnancy-induced hypertension and a history of asthma was also found (chi2 = 11.2, p = 0.001). However, after adjustment for potential confounders, this association failed to achieve statistical significance (adjusted odds ratio 1.2, 95% confidence interval 0.97 to 1.53, p = 0.083). CONCLUSION: Both pregnancy-induced hypertension and asthma might be caused by a third factor affecting smooth muscle reactivity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 12:51:26