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Titolo:
ELEVATED INTRAOCULAR-PRESSURE AND PSEUDOEXFOLIATION OF THE LENS CAPSULE AS RISK-FACTORS FOR CHRONIC OPEN-ANGLE GLAUCOMA - A POPULATION-BASED 5-YEAR FOLLOW-UP-STUDY
Autore:
EKSTROM C;
Indirizzi:
UNIV HOSP UPPSALA,DEPT OPHTHALMOL S-75185 UPPSALA SWEDEN UNIV UPPSALA,DEPT OPHTHALMOL S-75105 UPPSALA SWEDEN UNIV UPPSALA,CTR PRIMARY CARE RES,DEPT SOCIAL MED S-75105 UPPSALA SWEDEN
Titolo Testata:
Acta ophthalmologica
fascicolo: 2, volume: 71, anno: 1993,
pagine: 189 - 195
SICI:
0001-639X(1993)71:2<189:EIAPOT>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
OCULAR HYPERTENSION; PSEUDO-EXFOLIATION; MANIFEST GLAUCOMA;
Keywords:
OCULAR HYPERTENSION; PSEUDOEXFOLIATION; OPTIC DISC HEMORRHAGE; FOLLOW-UP STUDY; VISUAL FIELD DEFECT; AUTOMATIC PERIMETRY; OPEN-ANGLE GLAUCOMA; CHRONIC SIMPLE GLAUCOMA; CAPSULAR GLAUCOMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
C. Ekstrom, "ELEVATED INTRAOCULAR-PRESSURE AND PSEUDOEXFOLIATION OF THE LENS CAPSULE AS RISK-FACTORS FOR CHRONIC OPEN-ANGLE GLAUCOMA - A POPULATION-BASED 5-YEAR FOLLOW-UP-STUDY", Acta ophthalmologica, 71(2), 1993, pp. 189-195

Abstract

In 1984-86, a glaucoma survey was carried out in a municipality in central Sweden, comprising 760 subjects 65-74 years of age. Since 1988, a follow-up study of those 527 subjects who had normal and reliable visual fields has been in progress. A visual field defect was required for a diagnosis of chronic open-angle glaucoma. By December 1991, 10 cases of capsular glaucoma and 3 cases of chronic simple glaucoma had been found. The standardized relative risk for chronic open-angle glaucoma was 3.4 times (95% confidence interval: 1.1 - 11) greater in subjects with a baseline intraocular pressure greater-than-or-equal-to 21 mmHg, using the highest pressure in either eye, than in those with an intraocular pressure < 21 mmHg. Pseudoexfoliation increased the standardized relative risk 9.8-fold (95% confidence interval: 2.5 - 38). Therewas indication of effect modification between intraocular pressure and pseudoexfoliation. Optic disc haemorrhages were associated with a 4.8-fold (95% confidence interval: 0.63 - 37) increased unadjusted risk. The study supports the pressure theory of optic nerve damage in glaucoma. Pseudoexfoliation was recognized as an independent risk factor for the development of chronic open-angle glaucoma.

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Documento generato il 06/04/20 alle ore 07:27:57