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Titolo:
ARGININE VASOTOCIN GENE-EXPRESSION AND HORMONE SYNTHESIS DURING ONTOGENY OF THE CHICKEN-EMBRYO AND THE NEWBORN CHICK
Autore:
MUHLBAUER E; HAMANN D; XU B; IVELL R; UDOVIC B; ELLENDORFF F; GROSSMANN R;
Indirizzi:
INST SMALL ANIM RES,DORNBERGSTR 25-27 W-3100 CELLE GERMANY INST HORMONE & FERTIL RES W-2000 HAMBURG GERMANY
Titolo Testata:
Journal of neuroendocrinology
fascicolo: 3, volume: 5, anno: 1993,
pagine: 281 - 288
SICI:
0953-8194(1993)5:3<281:AVGAHS>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
GALLUS-DOMESTICUS; MESSENGER-RNA; RICH SEQUENCES; MESOTOCIN; VASOPRESSIN; PLASMA; SYSTEM; HYPOTHALAMUS; DEGRADATION; PITUITARY;
Keywords:
VASOTOCIN; ONTOGENY; GENE EXPRESSION; TRANSLATION; CHICKEN EMBRYO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
E. Muhlbauer et al., "ARGININE VASOTOCIN GENE-EXPRESSION AND HORMONE SYNTHESIS DURING ONTOGENY OF THE CHICKEN-EMBRYO AND THE NEWBORN CHICK", Journal of neuroendocrinology, 5(3), 1993, pp. 281-288

Abstract

Chicken embryos at different developmental stages (embryonal day (E) 6 to 21) and chicks at posthatch day 1 (Dl) were monitored for the development of their hypothalamo-neurohypophysial system as indicated by the kinetics of arginine vasotocin (AVT) gene expression via mRNA concentration and brain AVT content. Our data concerning the onset of geneexpression support previous results from our laboratory and others about an early activation of the AVT gene transcriptional and translational activity around E6. We could detect measurable amounts of AVT in chicken embryo brains at E6 and an exponential increase during further development until Dl. Dot blots of hypothalamic RNA extracts indicatedthat AVT gene transcript concentrations rose between E12 and E17 and slightly dropped thereafter. Northern hybridization showed that this drop was caused by a decrease of full length message and an increase ofsmaller transcripts during late embryonal and Dl stages, probably an AVT mRNA specific degradation phenomenon. The dissociation between theincrease of AVT concentration and AVT mRNA concentration visible at the Dl stage might be due to accumulation and storage of AVT in the magnocellular neurons, preferentially in their axon terminals in the neurohypophysis. Blood samples taken from E14 onwards revealed a constant increase in plasma osmolality and plasma AVT concentration. Our data suggest that, in the chicken, AVT seems to be required early during embryonal development, either for osmoregulatory or further unknown functions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 06:35:34