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Titolo:
LEFT SUPERIOR TEMPORAL BLOOD-FLOW INCREASES IN SCHIZOPHRENIC AND SCHIZOPHRENIFORM PATIENTS WITH AUDITORY HALLUCINATION - A LONGITUDINAL CASE-STUDY USING I-123 IMP SPECT
Autore:
SUZUKI M; YUASA S; MINABE Y; MURATA M; KURACHI M;
Indirizzi:
TOYAMA MED & PHARMACEUT UNIV,FAC MED,DEPT NEUROPSYCHIAT,2630 SUGITANITOYAMA 93001 JAPAN
Titolo Testata:
European archives of psychiatry and clinical neuroscience
fascicolo: 5, volume: 242, anno: 1993,
pagine: 257 - 261
SICI:
0940-1334(1993)242:5<257:LSTBII>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRAIN; METABOLISM; PATHOLOGY; VOLUME;
Keywords:
I-123-IMP SPECT; LEFT SUPERIOR TEMPORAL GYRUS; AUDITORY HALLUCINATION; SCHIZOPHRENIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
M. Suzuki et al., "LEFT SUPERIOR TEMPORAL BLOOD-FLOW INCREASES IN SCHIZOPHRENIC AND SCHIZOPHRENIFORM PATIENTS WITH AUDITORY HALLUCINATION - A LONGITUDINAL CASE-STUDY USING I-123 IMP SPECT", European archives of psychiatry and clinical neuroscience, 242(5), 1993, pp. 257-261

Abstract

Serial assessments of regional cerebral blood flow were performed using I-123-IMP SPECT in two schizophrenic and three schizophreniform patients with persistent auditory hallucination. The initial SPECT study in the period with prominent auditory hallucination revealed an increased accumulation of I-123-IMP in the left superior temporal area whichcorresponded to the auditory association cortex. In the follow-up SPECT study performed after clinical improvement, the distribution of I-123 IMP had normalized. One of the case with schizophrenia showed a similar increased uptake of I-123-IMP in the left superior temporal area in the third SPECT scan performed when a psychotic relapse with auditory hallucination occurred. MRI scans in two of the five patients demonstrated reduced volume of the temporal lobes. These findings suggest that the auditory hallucinations in schizophrenia may be involved in functional hyperactivity in the left superior temporal cortex which might be based partly on structural abnormalities in the temporal lobes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:27:36