Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
BORRELIA-BURGDORFERI MYOSITIS - REPORT OF 8 PATIENTS
Autore:
REIMERS CD; DEKONING J; NEUBERT U; PREACMURSIC V; KOSTER JG; MULLERFELBER W; PONGRATZ DE; DURAY PH;
Indirizzi:
UNIV MUNICH,CLIN INTERNAL MED INNENSTADT,FRIEDRICH BAUR INST,ZIEMSSENSTR 1A W-8000 MUNICH 2 GERMANY LAB VOLKSGEZONDHEIT FRIESLAND,DEPT PATHOL ANAT 8900 JA LEEUWARDEN NETHERLANDS MED CTR LEEUWARDEN,DEPT NEUROL 8934 JA LEEUWARDEN NETHERLANDS UNIV MUNICH,DEPT NEUROL W-8000 MUNICH 2 GERMANY UNIV MUNICH,DEPT DERMATOL W-8000 MUNICH 2 GERMANY FOX CHASE CANC CTR,DEPT PATHOL PHILADELPHIA PA 19111 UNIV MUNICH,DEPT HYG & MICROBIOL W-8000 MUNICH 2 GERMANY
Titolo Testata:
Journal of neurology
fascicolo: 5, volume: 240, anno: 1993,
pagine: 278 - 283
SICI:
0340-5354(1993)240:5<278:BM-RO8>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
LYME BORRELIOSIS; UNUSUAL MANIFESTATIONS; INFECTION; DISEASE; GOLD;
Keywords:
BORRELIA-BURGDORFERI; LYME DISEASE; MYOSITIS; IMMUNOHISTOLOGY; CULTURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
C.D. Reimers et al., "BORRELIA-BURGDORFERI MYOSITIS - REPORT OF 8 PATIENTS", Journal of neurology, 240(5), 1993, pp. 278-283

Abstract

Myositis is a rare manifestation of Lyme disease of unknown pathogenesis. This study describes the course of disease in eight patients withLyme disease, aged 37-70 years, all of whom were suffering from histologically proven myositis. The clinical, electrophysiological, and myopathological findings are reported. One patient showed signs and symptoms of myositis of all limbs. In six patients myositis was localized in the vicinity of skin lesions, arthritis or neuropathy caused by Borrelia burgdorferi. In another patient suffering from pronounced muscle weakness of the legs and cardiac arrest, inflammation of the myocardium, the conducting system and skeletal muscles was revealed at autopsy. Muscle biopsy revealed lymphoplasmocellular infiltrates combined withfew fibre degenerations in three patients. The lymphoplasmocellular infiltrates were found predominantly in the vicinity of small vessels. Several spirochetes were stained in six of seven muscle biopsy samplesby means of the immunogold-silver technique. Culturing of B. Burgdorferi from the muscle biopsy samples was, however, unsuccessful. Antibiotic treatment succeeded in curing the myositis in four of six patients. In one patients signs and symptoms improved. One patient died from cardiac arrest caused by myocarditis and Guillain-Barre syndrome. The outcome is unknown in one patient. Clinical and myopathological findings indicate that Lyme myositis can be caused either by local spreading of B. burgdorferi or an unknown antigen or toxin from adjacent tissuesor haematogenously.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 18:00:31