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Titolo:
ULTRASTRUCTURAL HEPATOCELLULAR FEATURES ASSOCIATED WITH SEVERE HEPATIC LIPIDOSIS IN CATS
Autore:
CENTER SA; GUIDA L; ZANELLI MJ; DOUGHERTY E; CUMMINGS J; KING J;
Indirizzi:
CORNELL UNIV,NEW YORK STATE COLL VET MED ITHACA NY 14853
Titolo Testata:
American journal of veterinary research
fascicolo: 5, volume: 54, anno: 1993,
pagine: 724 - 731
SICI:
0002-9645(1993)54:5<724:UHFAWS>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
PEROXISOME PROLIFERATORS; LIVER; ACIDS; METABOLISM; CARNITINE; DISEASE; CELL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
S.A. Center et al., "ULTRASTRUCTURAL HEPATOCELLULAR FEATURES ASSOCIATED WITH SEVERE HEPATIC LIPIDOSIS IN CATS", American journal of veterinary research, 54(5), 1993, pp. 724-731

Abstract

In this study, we compared hepatic ultrastructure in healthy cats, incats with severe hepatic lipidosis, and in cats with experimentally induced, chronic, extrahepatic bile duct occlusion. Ultrastructural features unique to the lipidosis syndrome included an apparent reduction in number of peroxisomes and alteration in their morphologic features. The quantity of endoplasmic reticulum, Golgi complexes, and lysosomeswas subjectively reduced, and paucity of cytosolic glycogen was observed, Bile canaliculi appeared collapsed because of cytosolic distention with lipid. Mitochondria were reduced in number and were markedly pleomorphic. Cristae assumed a variety of shapes, lengths, and orientations. Ultrastructural features of bile duct occlusion were similar to those described in other species and differed from those in cats with hepatic lipidosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/10/20 alle ore 13:36:59