Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
EFFECTS OF HYPERCHOLECYSTOKININEMIA PRODUCED BY PANCREATICOBILIARY DIVERSION ON PANCREATIC GROWTH AND ENZYME MESSENGER-RNA LEVELS IN STARVED RATS
Autore:
CHEN D; ANDERSSON K; IOVANNA JL; DAGORN JC; HAKANSON R;
Indirizzi:
UNIV LUND,DEPT PHARMACOL,SOLVEGATAN 10 S-22362 LUND SWEDEN UNIV LUND,DEPT PHARMACOL,SOLVEGATAN 10 S-22362 LUND SWEDEN NATL INST HLTH & MED RES,UNITE 315 MARSEILLE FRANCE ASTRA HASSLE AB,PRECLIN RES DEPT MOLNDAL SWEDEN
Titolo Testata:
Scandinavian journal of gastroenterology
fascicolo: 4, volume: 28, anno: 1993,
pagine: 311 - 314
SICI:
0036-5521(1993)28:4<311:EOHPBP>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLECYSTOKININ-PANCREOZYMIN; ANTAGONIST L-364,718; GENE-EXPRESSION; SEQUENCE; AMYLASE;
Keywords:
CHOLECYSTOKININ; FASTING; PANCREAS; PANCREATICOBILIARY DIVERSION; RATS; MESSENGER RNA; TROPHIC EFFECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
D. Chen et al., "EFFECTS OF HYPERCHOLECYSTOKININEMIA PRODUCED BY PANCREATICOBILIARY DIVERSION ON PANCREATIC GROWTH AND ENZYME MESSENGER-RNA LEVELS IN STARVED RATS", Scandinavian journal of gastroenterology, 28(4), 1993, pp. 311-314

Abstract

The purpose of the present study was to examine the weight, DNA content, and enzyme mRNA levels in the pancreas in response to endogenous hypercholecystokininemia produced by pancreaticobiliary diversion (PBD)in starved rats. The results showed that PBD, which is known to increase the circulating cholecystokinin (CCK) concentration, prevented thereduction in the weight and DNA content of the pancreas after 3 days of starving, and that PBD increased the mRNA levels of amylase, chymotrypsinogen B, and procarboxypeptidase A in the pancreas of starved rats. The findings support the view that endogenous CCK plays an important role in maintaining the weight of the normal pancreas of starved rats and that it stimulates the transcription of genes coding for pancreatic exocrine enzymes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:22:45