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Titolo:
PARENTAL SMOKING AND RISK OF CHILDHOOD BRAIN-TUMORS
Autore:
GOLD EB; LEVITON A; LOPEZ R; GILLES FH; HEDLEYWHYTE ET; KOLONEL LN; LYON JL; SWANSON GM; WEISS NS; WEST D; ASCHENBRENER C; AUSTIN DF;
Indirizzi:
UNIV CALIF DAVIS,ITEH,DIV OCCUPAT & ENVIRONM MED DAVIS CA 95616 CHILDRENS HOSP MED CTR BOSTON MA 02115 HARVARD UNIV,SCH MED BOSTON MA 02115 CHILDRENS HOSP LOS ANGELES LOS ANGELES CA 00000 UNIV SO CALIF LOS ANGELES CA 90089 CANC RES CTR HAWAII HONOLULU HI 00000 UNIV UTAH SALT LAKE CITY UT 84112 MICHIGAN STATE UNIV E LANSING MI 48824 UNIV WASHINGTON SEATTLE WA 98195 FRED HUTCHINSON CANC RES CTR SEATTLE WA 98104 NO CALIF CANC REGISTRY ALAMEDA CA 00000 UNIV IOWA,COLL MED IOWA CITY IA 52242 CALIF DEPT HLTH SERV EMERYVILLE CA 00000
Titolo Testata:
American journal of epidemiology
fascicolo: 6, volume: 137, anno: 1993,
pagine: 620 - 628
SICI:
0002-9262(1993)137:6<620:PSAROC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPLORATORY CASE-CONTROL; ENVIRONMENTAL-FACTORS; PASSIVE SMOKING; CANCER; PREGNANCY; SMOKERS; WOMEN; EXPOSURE; ETIOLOGY; CHILDREN;
Keywords:
BRAIN NEOPLASMS; CHILD; ENVIRONMENTAL EXPOSURE; NEOPLASMS; OCCURRENCE; SMOKING; SMOKING, PASSIVE;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
E.B. Gold et al., "PARENTAL SMOKING AND RISK OF CHILDHOOD BRAIN-TUMORS", American journal of epidemiology, 137(6), 1993, pp. 620-628

Abstract

Data from a large, Population-based, case-control study were analyzedto assess the role of parental smoking in childhood brain tumors. Parents of 361 cases, newly diagnosed between January 1, 1977 and December 31, 1981 and ascertained from eight Surveillance, Epidemiology, and End Results (SEER) program registries, and 1,083 controls had been interviewed. No significant differences in risks were found to be associated with maternal or paternal smoking at any time (odds ratio (OR) = 0.92 for mothers and 1.06 for fathers), during the year of birth of thechild (which included both the prenatal and postnatal periods) (ORs =0.84 for <1 pack/day and 1.0 for greater-than-or-equal-to 1 pack/day for mothers, and 0.68 for <1 pack/day and 1.07 for greater-than-or-equal-to 1 pack/day for fathers), or 2 years before the child was born, i.e., the pre-conception period (ORs = 0.75 for <1 pack/day and 1.01 for greater-than-or-equal-to 1 pack/day for mothers, and 0.90 for <1 pack/day and 1.1 5 for greater-than-or-equal-to 1 pack/day for fathers). Mothers were also specifically asked if they smoked during the pregnancy, and no association was found compared with never smokers (OR = 1.08, 95% confidence interval (Cl) 0.80-1.45) or for ever-smokers who continued to smoke during pregnancy compared with those who stopped smoking during pregnancy (OR = 1.15, 95% Cl 0.75-1.78). Finally, no significant increase in risk of brain tumors was found for the child's passive exposure to parental smoking during the period from birth to diagnosis of the brain tumor in the case. The lack of an effect of parental smoking was observed for both the major histologic types and locations of brain tumors. These findings and those from earlier studies provideno support for the hypothesis that parental cigarette smoking influences the risk of brain tumors in children.

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Documento generato il 07/07/20 alle ore 12:53:21