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Titolo:
TREATMENT OF MALIGNANT PERITONEAL EFFUSION IN DIGESTIVE AND OVARIAN-CANCER
Autore:
GILLY FN; CARRY PY; BRACHET A; SAYAG AC; PANTEIX G; SALLE B; BIENVENU J; BANSSILLON V; BURGARD G; MANCHON M; ROCHETTE A; BRAILLON G;
Indirizzi:
CTR HOSP LYON SUD,DEPT GEN & THORAC SURG F-69310 PIERRE BENITE FRANCE
Titolo Testata:
Medical oncology and tumor pharmacotherapy
fascicolo: 4, volume: 9, anno: 1992,
pagine: 177 - 181
SICI:
0736-0118(1992)9:4<177:TOMPEI>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
F.N. Gilly et al., "TREATMENT OF MALIGNANT PERITONEAL EFFUSION IN DIGESTIVE AND OVARIAN-CANCER", Medical oncology and tumor pharmacotherapy, 9(4), 1992, pp. 177-181

Abstract

Intra Peritoneal Chemo Hyperthermia (IPCH) with Mitomycin C (MMC) or Cisplatinum (CP) was used to treat 32 patients with far advanced digestive or ovarian cancers and peritoneal carcinomatosis. Surgical resection of the primary tumor has been possible in 18 cases. After closure of the abdominal wall, a 90 minutes IPCH was performed under general anaesthesia and 32-degrees-C general hypothermia, through 3 intraperitoneal drainages realizing a closed circuit, using 10 mg/l of MMC or 15 to 25 mg/l of CP in 6 1 of peritoneal dialysate heated at the inflow temperature of 46 to 49-degrees-C. The mortality rate was 3% and the morbidity rate was 3%. In 11 out of 12 patients with preoperative malignant ascites, no more ascites could be found after IPCH. For peritonealcarcinomatosis from digestive origin, median survival was 11.2 monthsand 1 year survival rate was 46.9%. These encouraging preliminary results show that IPCH is a safe and reliable treatment for peritoneal carcinomatosis in far advanced digestive or ovarian cancers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:40:51