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Titolo:
EXPRESSION OF C-FOS AND C-MYC GENES IN UTERUS AND NONREPRODUCTIVE ORGANS DURING THE IMPLANTATION PERIOD IN THE RAT
Autore:
VERNEAUX V; JOUVENOT M; COMPAGNONE P; PROPPER AY; ADESSI GL;
Indirizzi:
INSERM,U198,240 ROUTE DE DOLE F-25000 BESANCON FRANCE
Titolo Testata:
Biochemistry and cell biology
fascicolo: 2, volume: 70, anno: 1992,
pagine: 142 - 148
SICI:
0829-8211(1992)70:2<142:EOCACG>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTO-ONCOGENE; GROWTH-FACTORS; PROTOONCOGENE; TRANSCRIPTION; INDUCTION; CELLS; ACID;
Keywords:
PREGNANCY; IMPLANTATION; UTERUS; NONREPRODUCTIVE ORGANS; C-FOS; C-MYC;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
V. Verneaux et al., "EXPRESSION OF C-FOS AND C-MYC GENES IN UTERUS AND NONREPRODUCTIVE ORGANS DURING THE IMPLANTATION PERIOD IN THE RAT", Biochemistry and cell biology, 70(2), 1992, pp. 142-148

Abstract

The c-fos and c-myc mRNA levels were investigated in the uterus and nonreproductive organs of rats during the implantation period (from day5 to 7 of pregnancy). They were determined by densitometric analysis of slot blots and the mean values (n = 4) at a defined age of pregnancy were compared with those observed in nonpregnant control rats (NP group). No significant variations of c-fos level were observed in the liver and brain of pregnant rats. In the uterus, the c-fos level decreased, reached a minimum on day 6 (4-fold decrease compared with the NP group), and then increased. The c-fos level significantly increased in the kidney (2- and 2.5-fold on days 6 and 7), and in the lung (2.5-fold on day 7). The c-myc level did not significantly vary in the uterus,liver, and lung. It significantly increased in the kidney (3-fold on day 7) and in the brain (4.1-, 3.8-, and 6-fold, on days 5, 6, and 7). The changes in c-fos and (or) c-myc gene expression in the uterus andnonreproductive organs could be due to sexual steroids and (or) systemic factors from uterine cells or blastocysts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 12:45:01