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Titolo:
DAYTIME AND NIGHTTIME CONTENT OF MONOAMINES AND THEIR METABOLITES IN THE PINEAL-GLAND OF RAT AND HAMSTER
Autore:
HERMES B; HIEMKE C; REUSS S;
Indirizzi:
UNIV MAINZ,DEPT PSYCHIAT,UNTERE ZAHLBACHER STR 8 D-55101 MAINZ GERMANY UNIV MAINZ,DEPT PSYCHIAT D-55101 MAINZ GERMANY UNIV MAINZ,DEPT ANAT D-55101 MAINZ GERMANY
Titolo Testata:
Neuroscience letters
fascicolo: 1-2, volume: 179, anno: 1994,
pagine: 119 - 122
SICI:
0304-3940(1994)179:1-2<119:DANCOM>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
CATECHOLAMINE SYNTHESIS; TYROSINE-HYDROXYLASE; DOPAMINE; PROJECTIONS; INCREASE; NEURONS;
Keywords:
CIRCADIAN VARIATION; CATECHOLAMINE; SEROTONIN; PINEAL GLAND; IMMUNOHISTOCHEMISTRY; TH; DBH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
B. Hermes et al., "DAYTIME AND NIGHTTIME CONTENT OF MONOAMINES AND THEIR METABOLITES IN THE PINEAL-GLAND OF RAT AND HAMSTER", Neuroscience letters, 179(1-2), 1994, pp. 119-122

Abstract

Day- and nighttime content of catecholamines, serotonin and their metabolites were measured in the pineal gland of Sprague-Dawley rats and Djungarian hamsters. In addition, monoamine turnover rates were determined in the hamster pineal gland following administration of alpha-methyl-p-tyrosine. Animals were decapitated in the middle of the light ordark period, respectively, and pineal tissue was analysed by high performance liquid chromatography with electrochemical detection. Pinealsof both species exhibited day/night-differences in serotonin, 5-hydroxyindole-3-acetic acid and dopamine content. The hamster pineal gland further showed day/night differences in its content of epinephrine and3-methoxy-4-hydroxyphenylethyleneglycol. The dopamine turnover rate was augmented at night, while norepinephrine turnover was constant. Immunohistochemical incubations of pineal paraffine sections showed fibers and terminals stained by antisera to tyrosine-hydroxylase (TH) and dopamine-beta-hydroxylase, and a few perikarya-like structures exhibiting TH immunoreactivity. The results support the view that dopamine, rather than only functioning as a norepinephrine precursor, is actively involved in the control of melatonin synthesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 16:16:45