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Titolo:
CORONARY FLOW DYNAMICS AND RESERVE ASSESSED BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY IN OBSTRUCTIVE HYPERTROPHIC - CARDIOMYOPATHY
Autore:
MEMMOLA C; ILICETO S; NAPOLI VF; CAVALLARI D; SANTORO G; RIZZON P;
Indirizzi:
UNIV BARI,INST CARDIOL,POLICLIN,PIAZZA G CESARE I-70124 BARI ITALY UNIV BARI,INST CARDIOL,POLICLIN I-70124 BARI ITALY
Titolo Testata:
The American journal of cardiology
fascicolo: 11, volume: 74, anno: 1994,
pagine: 1147 - 1151
SICI:
0002-9149(1994)74:11<1147:CFDARA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULSED DOPPLER-ECHOCARDIOGRAPHY; VENTRICULAR DIASTOLIC FUNCTION; BLOOD-FLOW; NONINVASIVE ASSESSMENT; AORTIC-STENOSIS; VELOCITY; ARTERIES; CIRCULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
C. Memmola et al., "CORONARY FLOW DYNAMICS AND RESERVE ASSESSED BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY IN OBSTRUCTIVE HYPERTROPHIC - CARDIOMYOPATHY", The American journal of cardiology, 74(11), 1994, pp. 1147-1151

Abstract

Myocardial ischemia is frequently associated with left ventricular outflow obstruction. To assess coronary flow impairment in obstructive hypertrophic cardiomyopathy (HC), 10 patients with echo-Doppler-detected obstructive HC and normal coronary arteries underwent transesophageal echo-Doppler examination of both coronary flow velocity (CFV) at rest, recorded in the proximal left anterior descending coronary artery, and coronary now reserve (CFR) evaluated by means of dipyridamole infusion response. Ten normal patients were similarly studied and served as a control group. Two relevant alterations in coronary flow dynamics were detected in patients with HC: (1) a significantly increased diastolic/systolic CFV ratio, and (2) a significantly reduced dipyridamole/baseline CFV ratio. Compared with normal subjects, the CRI pattern showed a significantly greater diastolic and a significantly lower systolic component at rest (in some patients it was reversed). Diastolic/systolic CRI ratio was significantly higher in pa tients with HC at baseline (3.1 +/- 1 vs 1.6 +/- 0.5; p < 0.01) and increased further after dipyridamole infusion (4.9 +/- 2 vs 2.2 +/- 0.7; p < 0.01). In addition, CFR was impaired in patients with HC (1.8 +/- 0.3 vs 3.1 +/- 0.5; p < 0.01). Furthermore, a significant correlation between CFR and intraventricular pressure gradient was found. Thus, transesophageal echo-Doppler examination is a useful tool for evaluating CFV dynamics and CFR as demonstrated in patients with obstructive HC.

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Documento generato il 04/12/20 alle ore 19:50:02