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Titolo:
HORMONALLY ACTIVE PEPTIDES IN HUMAN-MILK
Autore:
KOLDOVSKY O;
Indirizzi:
ARIZONA HLTH SCI CTR,DEPT PEDIAT TUCSON AZ 85724 UNIV ARIZONA,COLL MED,DEPT PEDIAT TUCSON AZ 00000 UNIV ARIZONA,COLL MED,DEPT PHYSIOL TUCSON AZ 85724 UNIV ARIZONA,COLL MED,STEELE MEM RES CTR TUCSON AZ 00000 UNIV ARIZONA,COLL MED,FURROW RES LAB TUCSON AZ 00000
Titolo Testata:
Acta paediatrica
, volume: 83, anno: 1994, supplemento:, 402
pagine: 89 - 93
SICI:
0803-5253(1994)83:<89:HAPIH>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPIDERMAL GROWTH-FACTOR; TRANS-EPITHELIAL TRANSPORT; SUCKLING RAT ILEUM; FACTOR-I; GASTROINTESTINAL-TRACT; BOVINE COLOSTRUM; NEONATAL RATS; PROMOTING ACTIVITY; FACTOR RECEPTORS; BINDING-PROTEIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
106
Recensione:
Indirizzi per estratti:
Citazione:
O. Koldovsky, "HORMONALLY ACTIVE PEPTIDES IN HUMAN-MILK", Acta paediatrica, 83, 1994, pp. 89-93

Abstract

Human milk contains many hormone and hormone-like peptides. The gastrointestinal tract of newborn infants exhibits lower proteolytic activity than in adults and higher ''permeability'' for macromolecules. Studies in experimental animals demonstrate that several peptides (epidermal growth factors, insulin-like growth factor I and bombesin) after orogastric administration exhibit effects on the small intestine and other organs (liver or pancreas). Few studies performed in human neonatessuggest a ''survival'' of epidermal growth factor in their gastric content. Further studies are needed to evaluate the role of milk-borne hormonally active peptides. This need is stressed by the fact that several of those known to be present in human milk were found to be low ornot detectable in infant formulae (epidermal growth factor, insulin-like growth factor I, insulin, parathyroid hormone-related peptide).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 14:20:38