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Titolo:
RELATION BETWEEN LEFT-VENTRICULAR HYPERTR OPHY AND RETINOVASCULAR CHANGES IN MILD HYPERTENSION
Autore:
REINO AP; GONZALEZJUANATEY JR; CASTROVIEJO M; VALDES L; ESTEVEZ JC; MENDEZ I; CABEZASCERRATO J;
Indirizzi:
HOSP CONXO,MED INTERNA SERV,COMPLEJO HOSP SANTIAGO,R BALTAR S-N SANTIAGO COMPOSTE 15706 SPAIN HOSP CONXO,SERV CARDIOL,COMPLEJO HOSP SANTIAGO SANTIAGO COMPOSTE 15706 SPAIN HOSP CONXO,SERV OFTALMOL,COMPLEJO HOSP SANTIAGO SANTIAGO COMPOSTE 15706 SPAIN UNIV SANTIAGO DE COMPOSTELA,DEPT ECONMETRIA LA CORUNA SPAIN
Titolo Testata:
Medicina Clinica
fascicolo: 8, volume: 108, anno: 1997,
pagine: 281 - 285
SICI:
0025-7753(1997)108:8<281:RBLHOA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
SPA
Soggetto:
CORONARY-ARTERY DISEASE; BLOOD-PRESSURE; MYOCARDIAL-INFARCTION; MODERATE HYPERTENSION; MASS; ARRHYTHMIAS; ASSOCIATION; ADAPTATION; HEALTH; MEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
A.P. Reino et al., "RELATION BETWEEN LEFT-VENTRICULAR HYPERTR OPHY AND RETINOVASCULAR CHANGES IN MILD HYPERTENSION", Medicina Clinica, 108(8), 1997, pp. 281-285

Abstract

BACKGROUND: To evaluate the possible relation between left ventricular hypertrophy and vascular changes in retine, in patients with mild hypertension. PATIENTS AND METHODS: We established a group with 51 hypertensives (27 males and 24 females), with essential mild hypertension, which had never been treated. An ambulatory monitoring blood pressure,24 hours electrocardiographic monitoring, echocardiography and funduscopy were realized to all of them. RESULTS: Fifty-five per cent of thehypertensives had retinopathy grades I-II. We established two subgroups with and without retinopathy, The age, systolic, diastolic and meanblood pressures, so as body mass index were higher in the group with retinovascular damage. No significant differences were observed in theecographic parameters between two subgroups except the interventricular septal thickness (10.5 +/- 2.1 mm in the subgroup without vs 11.1 +/- 2.3 mm in the subgroup with retinovascular damage) (p < 0.05), As 24-hour maximum and mean systolic and diastolic blood pressure, daytimemean systolic blood pressure (SBP) and diastolic blood pressure (DBP), daytime and night-time DBP load, as daytime SEP load were higher in the hypertensive patients with retinovascular changes, There was echocardiographic left ventricular hypertrophy in 51% of the hypertensive patients, without differences between both subgroups of hypertensive patients. Body mass index (g/m) correllated significantly (p < 0.01) with the retinovascular damage. In the multivariant analysis, male as well female, the funduscopy correllated with left ventricular mass index (g/m(2)). We established a discriminant function to separate hypertensives with and without left ventricular hypertrophy and another to separate hypertensives with and without retinopathy. Both functions included body mass index and maximum SEP, so as daytime SEP load and nighttime mean DBP to the left ventricular hypertrophy function. CONCLUSIONS:Left ventricular hypertrophy and retinovascular damage appear early in the course of blood pressure elevation and both changes develop in parallel, Our results indicate that there exists a relation between both cardiac and vascular changes in the hypertension. Body mass index and maximum SEP, appear to be important determinants of structural adaptation in mild hypertension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 22:32:10