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Titolo:
3-BETA-HYDROXYSTEROID DEHYDROGENASE-ACTIVITY AND GESTAGEN CONCENTRATIONS IN BOVINE COTYLEDONS AND CARUNCLES DURING GESTATION AND PARTURITION
Autore:
TSUMAGARI S; KAMATA J; TAKAGI K; TANEMURA K; YOSAI A; TAKEISHI M;
Indirizzi:
NIHON UNIV,DEPT VET OBSTET & GYNECOL,1866 KAMEINO FUJISAWA KANAGAWA 252 JAPAN
Titolo Testata:
Journal of Reproduction and Fertility
fascicolo: 1, volume: 102, anno: 1994,
pagine: 35 - 39
SICI:
0022-4251(1994)102:1<35:3DAGC>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROGESTERONE; FETAL; COWS; PLACENTOMES; SECRETION; PREGNANCY; PLASMA; BLOOD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
S. Tsumagari et al., "3-BETA-HYDROXYSTEROID DEHYDROGENASE-ACTIVITY AND GESTAGEN CONCENTRATIONS IN BOVINE COTYLEDONS AND CARUNCLES DURING GESTATION AND PARTURITION", Journal of Reproduction and Fertility, 102(1), 1994, pp. 35-39

Abstract

3 beta-Hydroxysteroid dehydrogenase (3 beta-HSD) activity in bovine cotyledons was much higher than in caruncles throughout the gestation period. The activity of this enzyme in cotyledons increased greatly to 150.6 +/- 5.8 pmol min(-1) mg(-1) protein during the seventh mg month of gestation, reached a peak of 221.0 +/- 34.9 pmol min(-1) mg(-1) protein during the mg eighth month, and decreased at parturition. Progesterone and 20 alpha-hydroxyprogesterone concentrations in cotyledons also increased sharply to 2.69 +/- 0.30 and 2.15 +/- 0.42 ng mg(-1) protein, respectively, during the seventh month of gestation, reaching peaks of 2.86 +/- 0.47 and 2.51 +/- 0.36 ng mg(-1) protein, respectively,during the eighth month and decreasing at parturition, in a manner similar to the activity of 3 beta-hydroxysteroid dehydrogenase. The fluctuation of 17 alpha-hydroxyprogesterone concentration in cotyledons was different from that of progesterone and 20 alpha-hydroxyprogesterone. These findings indicate that the activity of 3 beta-hydroxysteroid dehydrogenase in the placenta is enhanced during the third trimester, and progesterone synthesized in the cotyledons is converted concurrently to 20 alpha-hydroxyprogesterone before progesterone is transferred to the fetal blood.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 15:47:33