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Titolo:
TULA VIRUS - A NEWLY DETECTED HANTAVIRUS CARRIED BY EUROPEAN COMMON VOLES
Autore:
PLYUSNIN A; VAPALAHTI O; LANKINEN H; LEHVASLAIHO H; APEKINA N; MYASNIKOV Y; KALLIOKOKKO H; HENTTONEN H; LUNDKVIST A; BRUMMERKORVENKONTIO M; GAVRILOVSKAYA I; VAHERI A;
Indirizzi:
UNIV HELSINKI,HAARTMAN INST,DEPT VIROL,POB 21 SF-00014 HELSINKI FINLAND FINNISH FOREST RES INST,DEPT FOREST ECOL SF-01301 VANTAA FINLAND MOSCOW POLIOMYELITIS & VIRAL ENCEPHALITIS RES INS MOSCOW 142782 RUSSIA SWEDISH INST INFECT DIS CONTROL,DEPT DEF MICROBIOL S-10521 STOCKHOLM SWEDEN
Titolo Testata:
Journal of virology
fascicolo: 12, volume: 68, anno: 1994,
pagine: 7833 - 7839
SICI:
0022-538X(1994)68:12<7833:TV-AND>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROSPECT-HILL VIRUS; HEMORRHAGIC-FEVER; RENAL SYNDROME; MOLECULAR CHARACTERIZATION; NEPHROPATHIA-EPIDEMICA; GENOMIC SEGMENT; HANTAAN VIRUS; BANK VOLES; S-GENOME; INFECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
54
Recensione:
Indirizzi per estratti:
Citazione:
A. Plyusnin et al., "TULA VIRUS - A NEWLY DETECTED HANTAVIRUS CARRIED BY EUROPEAN COMMON VOLES", Journal of virology, 68(12), 1994, pp. 7833-7839

Abstract

A novel hantavirus has been discovered in European common voles, Microtus arvalis and Microtus rossiaemeridionalis. According to sequencingdata for the genomic RNA S segment and nucleocapsid protein and data obtained by immunoblotting with a panel of monoclonal antibodies, the virus, designated Tula virus, is a distinct novel member of the genus Hantavirus. Phylogenetic analyses of Tula virus indicate that it is most closely related to Prospect Hill, Puumala, and Muerto Canyon viruses. The results support the view that the evolution of hantaviruses follows that of their primary carriers. Comparison of strains circulatingwithin a local rodent population revealed a genetic drift via accumulation of base substitutions and deletions or insertions. The Tula virus population from individual animals is represented by quasispecies, indicating the potential for rapid evolution of the agent.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/10/20 alle ore 23:44:48