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Titolo:
STRESS AND IMMUNITY - REVIEW OF STUDIES I N PSYCHONEUROIMMUNOLOGY
Autore:
FILLION L; KIROUAC G; LEMYRE L; MANDEVILLE R;
Indirizzi:
UNIV OTTAWA,ECOLE PSYCHOL OTTAWA K1N 6N5 ONTARIO CANADA UNIV OTTAWA,ECOLE PSYCHOL OTTAWA K1N 6N5 ONTARIO CANADA UNIV MIAMI,DEPT PSYCHOL CORAL GABLES FL 33124 UNIV OTTAWA,ECOLE PSYCHOL OTTAWA K1N 6N5 ONTARIO CANADA UNIV QUEBEC,INST ARMAND FRAPPIER LAVAL H7N 4Z3 QUEBEC CANADA
Titolo Testata:
Canadian psychology
fascicolo: 4, volume: 35, anno: 1994,
pagine: 405 - 426
SICI:
0708-5591(1994)35:4<405:SAI-RO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
FRE
Soggetto:
KILLER-CELL-ACTIVITY; T POLYCLONAL PROLIFERATION; LIFE EVENTS; SOCIAL SUPPORT; PERSONAL CONTROL; CANCER-PATIENTS; BREAST-CANCER; LYMPHOCYTE-PROLIFERATION; INDIVIDUAL-DIFFERENCES; IMMUNOLOGICAL CHANGES;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Citazioni:
133
Recensione:
Indirizzi per estratti:
Citazione:
L. Fillion et al., "STRESS AND IMMUNITY - REVIEW OF STUDIES I N PSYCHONEUROIMMUNOLOGY", Canadian psychology, 35(4), 1994, pp. 405-426

Abstract

The thesis of a systemic link between stress and health has been around for a long time. Psychoneuroimmunology (PNI) is a new interdisciplinary field offering promising avenues for major developments in stressresearch. PNI focuses on the relationships between the nervous, endocrine and immune systems. It aims, among other objectives, at providingan explanation for the role of psychosocial factors in individual resistance to illnesses. Classic contributors to PNI have put forward four major propositions about the link between stress and immunity. They stated that (1) psychosocial stressors caused an immunosuppressive response, (2) this immunosuppressive response was observable under intense and enduring stress, (3) the immunosuppressive response led to increased vulnerability to illnesses, and (4) an improvement on stress state yielded to an increase in immune response. Recent studies either in the laboratory or in the field have provided empirical evidence for these hypotheses in humans. The objective of this paper is to review empirical work relating immunity and stress as measured in terms of state, stressors or cognitive appraisal. Following a brief definition of psychological stress in a transactional perspective, a presentation of the immune system and its physiological interconnections, fifty studiesin human PNI published since 1985 are introduced according to the type of contributions their design provided. Then a critical analysis is suggested along with identification of common findings and finally a discussion of the four propositions. Hypothesis 1 is supported in termsof immunomodulation while Hypothesis 2 is contradicted by the observation that short term laboratory stressors are sufficient to induce immunomodulation. Not much evidence exist as yet to establish increased vulnerability to illnesses, as stated by Hypothesis 3. Finally, clinical studies suggest possibilities to increase or restore immune responses.

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Documento generato il 09/08/20 alle ore 22:48:40