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Titolo:
REAPPRAISAL OF RASMUSSENS-SYNDROME WITH SPECIAL EMPHASIS ON TREATMENTWITH HIGH-DOSES OF STEROIDS
Autore:
CHINCHILLA D; DULAC O; ROBAIN O; PLOUIN P; PONSOT G; PINEL JF; GRABER D;
Indirizzi:
HOP ST VINCENT DE PAUL,DEPT NEUROPEDIAT,82 AV DENFERT ROCHEREAU F-75674 PARIS 14 FRANCE HOP ST VINCENT DE PAUL,DEPT NEUROPEDIAT F-75674 PARIS 14 FRANCE CHU RENNES,INSERM,U29 RENNES FRANCE CHU RENNES,DEPT NEUROPHYSIOL RENNES FRANCE CHU RENNES,DEPT NEUROL RENNES FRANCE HOSP PURPAN TOULOUSE FRANCE
Titolo Testata:
Journal of Neurology, Neurosurgery and Psychiatry
fascicolo: 11, volume: 57, anno: 1994,
pagine: 1325 - 1333
SICI:
0022-3050(1994)57:11<1325:RORWSE>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOCALIZED ENCEPHALITIS RASMUSSENS; EPILEPSIA PARTIALIS CONTINUA; MULTIPLE-SCLEROSIS; PULSED METHYLPREDNISOLONE; INTRAVENOUS METHYLPREDNISOLONE; RHEUMATOID-ARTHRITIS; CHILDHOOD; THERAPY; CYTOMEGALOVIRUS; SEIZURES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
48
Recensione:
Indirizzi per estratti:
Citazione:
D. Chinchilla et al., "REAPPRAISAL OF RASMUSSENS-SYNDROME WITH SPECIAL EMPHASIS ON TREATMENTWITH HIGH-DOSES OF STEROIDS", Journal of Neurology, Neurosurgery and Psychiatry, 57(11), 1994, pp. 1325-1333

Abstract

Eight patients with Rasmussen's syndrome and epilepsia partialis continua were treated with high doses of steroids, including pulses of methylprednisolone and prednisone in decreasing doses. Three patients exhibited clinical, radiological, or histological evidence of bilateral involvement. Epilepsy and focal deficit decreased within six months in seven patients. Only five patients, in whom steroid treatment had begun less than 15 months after the onset of epilepsia partialis continua,experienced a lasting effect although they had periodic episodes of transient relapse. Treatment with high doses of steroids seems advisable during the first year after onset of epilepsia partialis continua, before hemiplegia has developed and in cases with bilateral involvement.

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Documento generato il 05/04/20 alle ore 03:35:11