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Titolo:
HIDDEN DYNAMICS IN RAPID CHANGES OF BILAYER SHAPE
Autore:
EVANS E; YEUNG A;
Indirizzi:
UNIV BRITISH COLUMBIA,DEPT PHYS,6224 AGR RD VANCOUVER V6T 1W5 BC CANADA UNIV BRITISH COLUMBIA,DEPT PATHOL VANCOUVER V6T 1W5 BC CANADA
Titolo Testata:
Chemistry and physics of lipids
fascicolo: 1-2, volume: 73, anno: 1994,
pagine: 39 - 56
SICI:
0009-3084(1994)73:1-2<39:HDIRCO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENTROPY-DRIVEN TENSION; RED-BLOOD-CELLS; FLUID MEMBRANES; PHOSPHOLIPID-VESICLES; CURVATURE ELASTICITY; PHYSICAL-PROPERTIES; ADHESION; FLUCTUATIONS; MODEL; TRANSFORMATIONS;
Keywords:
BILAYER MECHANICS; VESICLE SHAPE DYNAMICS; STRATIFIED MEMBRANES; INTERLAYER COUPLING AND DISSIPATION; VESICLE BILAYER TETHERS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
E. Evans e A. Yeung, "HIDDEN DYNAMICS IN RAPID CHANGES OF BILAYER SHAPE", Chemistry and physics of lipids, 73(1-2), 1994, pp. 39-56

Abstract

In the past, mechanical models for lipid bilayers have been conceptualized on the basis that the membrane is a 'unit' structure where energy is coupled to deformation through single fields for surface curvature and density - valid only for chemically bonded layers. By comparison, real bilayers are composed of two weakly adherent monolayers that can move slowly past one another with negligible input of local energy if shape remains constant. However, when bilayer shape changes rapidly,an unexpected viscous impedance arises from relative motion between layers, which significantly augments conventional retardation by dissipation in hydrodynamic how. The added dissipation is produced by drag at the monolayer-monolayer interface. This leads to 'hidden dynamic coupling' of the layers through density differences that spread diffusively over the surface with long range consequences. Here, we examine theorigins of mechanical coupling between layers in bilayers and show that evolution of the differential density between layers creates new dynamics previously overlooked in membrane behavior. To demonstrate the profound affect of dynamic coupling in bilayers, we describe a model situation (supported by experimental evidence) where a nanoscale tube of membrane is pulled rapidly from a macroscopic-size vesicle. Rapid extraction of bilayer through this 1000-fold increase in curvature creates an enormous relative motion between layers near the vesicle-tube junction (molecules in opposite layers slip past at rates approaching 10(5)/s) and, in rum, interlayer drag that dominates the extraction force.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 19:00:13