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Titolo:
THE PHARMACOTHERAPY OF BORDERLINE PERSONALITY-DISORDER
Autore:
NEW AS; TRESTMAN RL; SIEVER LJ;
Indirizzi:
WESTERN PSYCHIAT INST & CLIN,RM 1175,3811 OHARA ST PITTSBURGH PA 15243 BRONX VET AFFAIRS MED CTR,DEPT PSYCHIAT NEW YORK NY 00000 MT SINAI MED CTR NEW YORK NY 10029
Titolo Testata:
CNS DRUGS
fascicolo: 5, volume: 2, anno: 1994,
pagine: 347 - 354
SICI:
1172-7047(1994)2:5<347:TPOBP>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMPULSIVE AGGRESSIVE-BEHAVIOR; DSM-III; DIAGNOSTIC INTERVIEW; DOUBLE-BLIND; HALOPERIDOL; FLUOXETINE; PLACEBO; PHENELZINE; EFFICACY; LITHIUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
59
Recensione:
Indirizzi per estratti:
Citazione:
A.S. New et al., "THE PHARMACOTHERAPY OF BORDERLINE PERSONALITY-DISORDER", CNS DRUGS, 2(5), 1994, pp. 347-354

Abstract

Pharmacotherapy is used increasingly as a helpful adjunct to psychotherapeutic interventions in the treatment of borderline personality disorder. Clinical trials have been performed to investigate drug treatment of the 3 symptom clusters associated with borderline personality disorder - impulsivity, affective lability and psychotic-like symptoms. Although no single agent ameliorates all the symptoms of this diagnosis, and patients vary considerably in their response to medication, pharmacological strategies for each symptom can be delineated. Impulsivity and aggression can be treated with selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), lithium, beta-adrenoceptor blockers or antipsychotics. Affective symptomology has also been found to respond to MAOIs, SSRIs andlithium. Interestingly, patients with borderline personality disorderdo not seem to respond to tricyclic antidepressants. As would be expected, antipsychotics are the most effective medications for the treatment of the psychotic symptoms of borderline personality disorder. Various techniques to improve compliance and enhance the treatment alliance with the patient can be suggested, including patient education aboutthe role of the pharmacologist (and therapist) in treatment and aboutthe nature of agents prescribed. In addition, if possible, patients should be allowed to play an active part in the selection of drugs.

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Documento generato il 27/01/20 alle ore 17:01:27