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Titolo:
DIAGNOSTIC INTERVIEW FOR GENETIC-STUDIES - RATIONALE, UNIQUE FEATURES, AND TRAINING
Autore:
NURNBERGER JI; BLEHAR MC; KAUFMANN CA; YORKCOOLER C; SIMPSON SG; HARKAVYFRIEDMAN J; SEVERE JB; MALASPINA D; REICH T; MILLER M; BOWMAN ES; DEPAULO JR; CLONINGER CR; ROBINSON G; MODLIN S; GERSHON ES; MAXWELL E; GUROFF JJ; KIRCH D; WYNNE D; BERG K; TSUANG MT; FARAONE SV; PEPPLE JR; RITZ AL;
Indirizzi:
INDIANA UNIV,SCH MED,INST PSYCHIAT RES,DEPT PSYCHIAT,791 UNION DR INDIANAPOLIS IN 46202 INDIANA UNIV,MED CTR,DEPT PSYCHIAT INDIANAPOLIS IN 00000 COLUMBIA UNIV,DEPT PSYCHIAT NEW YORK NY 10032 JOHNS HOPKINS UNIV,DEPT PSYCHIAT BALTIMORE MD 00000 WASHINGTON UNIV,DEPT PSYCHIAT ST LOUIS MO 00000 NIMH,DIV CLIN & TREATMENT RES ROCKVILLE MD 20857 NIMH,INTRAMURAL RES PROGRAM ROCKVILLE MD 20857 BROCKTON W ROXBURY VET AFFAIRS MED CTR BROCKTON MA 00000 HARVARD UNIV,SCH MED BOSTON MA 00000 HARVARD UNIV,SCH PUBL HLTH BOSTON MA 02115 SRA TECHNOL INC FALLS CHURCH VA 00000
Titolo Testata:
Archives of general psychiatry
fascicolo: 11, volume: 51, anno: 1994,
pagine: 849 - 859
SICI:
0003-990X(1994)51:11<849:DIFG-R>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIFETIME PSYCHIATRIC-DIAGNOSIS; STRUCTURED CLINICAL INTERVIEW; AFFECTIVE-DISORDERS; FAMILIAL TRANSMISSION; 1ST-DEGREE RELATIVES; CAGE QUESTIONNAIRE; FOLLOW-UP; SCHIZOPHRENIA; DEPRESSION; RELIABILITY;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Science Citation Index Expanded
Citazioni:
60
Recensione:
Indirizzi per estratti:
Citazione:
J.I. Nurnberger et al., "DIAGNOSTIC INTERVIEW FOR GENETIC-STUDIES - RATIONALE, UNIQUE FEATURES, AND TRAINING", Archives of general psychiatry, 51(11), 1994, pp. 849-859

Abstract

This article reports on the development and reliability of the Diagnostic Interview for Genetic Studies (DIGS), a clinical interview especially constructed for the assessment of major mood and psychotic disorders and their spectrum conditions. The DIGS, which was developed and piloted as a collaborative effort of investigators from sites in the National Institute of Mental Health (NIMH) Genetics Initiative, has the following additional features: (1) polydiagnostic capacity; (2) a detailed assessment of the course of the illness, chronology of psychotic and mood syndromes, and comorbidity; (3) additional phenomenologic assessments of symptoms; and (4) algorithmic scoring capability. The DIGSis designed to be employed by interviewers who exercise significant clinical judgment and who summarize information-in narrative form as well as in ratings. A two-phase test-retest (within-site, between-site) reliability study was carried out for DSM-III-R criteria-based major depression, bipolar disorder, schizophrenia, and schizoaffective disorder. Reliabilities using algorithms were excellent (0.73 to 0.95), except for schizoaffective disorder, for which disagreement on estimates of duration of mood syndromes relative to psychosis reduced reliability. A final best-estimate process using medical records and information from relatives as well as algorithmic diagnoses is expected to be morereliable in making these distinctions. The DIGS should be useful as part of archival data gathering for genetic studies of major affective disorders, schizophrenia, and related conditions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 21:48:01