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Titolo:
ASSOCIATION OF CARDIAC AUTONOMIC FUNCTION AND THE DEVELOPMENT OF HYPERTENSION - THE ARC STUDY
Autore:
LIAO DP; CAI JW; BARNES RW; TYROLER HA; RAUTAHARJU P; HOLME I; HEISS G;
Indirizzi:
UNIV N CAROLINA,SCH PUBL HLTH,DEPT EPIDEMIOL,137 E FRANKLIN ST,306 NAT BANK PLAZA CHAPEL HILL NC 27514
Titolo Testata:
American journal of hypertension
fascicolo: 12, volume: 9, anno: 1996,
parte:, 1
pagine: 1147 - 1156
SICI:
0895-7061(1996)9:12<1147:AOCAFA>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-RATE-VARIABILITY; SPECTRAL-ANALYSIS;
Keywords:
HEART RATE VARIABILITY; AUTONOMIC FUNCTION; HYPERTENSION; COHORT STUDY; RACE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
D.P. Liao et al., "ASSOCIATION OF CARDIAC AUTONOMIC FUNCTION AND THE DEVELOPMENT OF HYPERTENSION - THE ARC STUDY", American journal of hypertension, 9(12), 1996, pp. 1147-1156

Abstract

To relate cardiac autonomic function measured by heart rate variability (HRV) with prevalent and incident hypertension at the population level, the authors examined a stratified random sample of 2,061 examinees from the biracial Atherosclerosis Risk in Communities (ARIC) cohort. Baseline, supine, resting beat-to-beat heart rate data were collected. High frequency (HF, 0.15 to 0.35 Hz), low frequency (LF, 0.025 to 0.15 Hz) spectral powers, and LF/HF ratio, estimated from spectral analysis, and standard deviation of all normal RR intervals (SDNN), calculated from time domain analysis, were used as the conventional indices of cardiac autonomic function. From this sample, 650 prevalent hypertensives were identified. Of those normotensive at baseline (n = 1,338), 64 participants developed hypertension during 3 years of follow-up. Inthe cross-sectional analysis, the adjusted geometric means of HF were1.26, 1.20, and 1.00 (beat/min)(2) for normotensives, untreated hypertensives, and treated hypertensives, respectively; means of LF were 3.24, 3.26, and 2.58; means of LF/HF ratio were 2.57, 2.70, and 2.56; and means of SDNN were 39, 34, and 35 (ms) respectively. In the prospective analysis, a statistically significant, graded inverse association between baseline HF and the risk of incident hypertension was observed: the adjusted incident odds ratios (95% CI) were 1.00, 1.46 (0.61, 3.46), 1.50 (0.65, 3.50) and 2.44 (1.15, 5.20) from the highest to the lowest quartile of HF. No clear pattern of association was observed forLF. Significant trends of association for LF/HF and SDNN and incidenthypertension were also found. These results suggest that cardiac autonomic function is associated with prevalent hypertension, and that reduced vagal function and the imbalance of sympatho-vagal function are associated with the risk of developing hypertension. (C) 1996 American Journal of Hypertension, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 06:58:51