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Titolo:
NEGATIVE 2ND-LOOK LAPAROTOMY - AN OVARIAN -CANCER ANALYSIS OF PROGNOSTIC AND SURVIVAL FACTORS BASED ON 64 CASES TREATED AT THE INSTITUT GUSTAVE-ROUSSY
Autore:
PAUTIER P; REY A; MICHEL G; CASTAIGNE D; ROCHARD F; DUVILLARD P; HAIEMEDER C; CURCIO P; BENEDETTIRICHARD L; LHOMME C;
Indirizzi:
INST GUSTAVE ROUSSY,SERV BIOSTAT,RUE CAMILLE DESMOULINS F-94800 VILLEJUIF FRANCE INST GUSTAVE ROUSSY,SERV CHIRURG GYNECOL F-94800 VILLEJUIF FRANCE INST GUSTAVE ROUSSY,SERV ANATOMOPATHOL F-94800 VILLEJUIF FRANCE INST GUSTAVE ROUSSY,SERV RADIOTHERAPIE & CURIETHERAPIE F-94800 VILLEJUIF FRANCE
Titolo Testata:
Bulletin du cancer
fascicolo: 2, volume: 84, anno: 1997,
pagine: 147 - 154
SICI:
0007-4551(1997)84:2<147:N2L-AO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
FRE
Soggetto:
2ND-LOOK LAPAROTOMY; CYTOREDUCTIVE SURGERY; RECURRENT DISEASE; CARCINOMA; TOMOGRAPHY; CHEMOTHERAPY; REASSESSMENT; MANAGEMENT; OPERATION;
Keywords:
OVARIAN ADENOCARCINOMA; NEGATIVE 2ND-LOOK LAPOROTOMY; PROGNOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
P. Pautier et al., "NEGATIVE 2ND-LOOK LAPAROTOMY - AN OVARIAN -CANCER ANALYSIS OF PROGNOSTIC AND SURVIVAL FACTORS BASED ON 64 CASES TREATED AT THE INSTITUT GUSTAVE-ROUSSY", Bulletin du cancer, 84(2), 1997, pp. 147-154

Abstract

This study describes 64 cases of ovarian adenocarcinoma seen in the Gustave-Roussy lnstitut between 1978 and 1988 and who had a negative second-look laparotomy. The median age was 51 years (30-74). FIGO stageswere: I: 7 (11%) II: 3 (5%); III: 39 (61%); IV:3 (5%); and undetermined: 12 (19%). There were 50% of serous type, 14% of endometrioid type,13% of undifferencied type, 8%, of clear cells type, 3% of mucinous type, and 3% of mixt type tumors There were 50% of grade 3 tumors. Initial debulking surgery was as complete as possible in 59 patients, witha residual tumor after surgery superior or equal to 2 cm in 25 patients. Post second-look surgery treatment (n = 57) consisted of chemotherapy (CT) alone in 22 patients (34%), radiotherapy (RT) alone in 31 patients (49%), and CT associated with RT in 4 patients (6%). Median follow-up is 100 months. The overall survival rates at 3 and 5 years were respectively 86 and 81%, and disease free survival rater 70 and 61%. Among the 64 patients, 26; relapsed (39%). Median time to relapse was 36 months. There is a statistical difference in the survival between patients who had no or inferior to 2 cm residual tumor and others. Residual tumor was the only factor to be significant in univariate and multivariate analysis of survival.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 07:56:56