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Titolo:
PLACEBO-RESPONSE IN AGGRESSIVE-CHILDREN WITH CONDUCT DISORDER
Autore:
SANCHEZ LE; ARMENTEROS JL; SMALL AM; CAMPBELL M; ADAMS PB;
Indirizzi:
NYU,MED CTR,DEPT PSYCHIAT,550 1ST AVE NEW YORK NY 10016 NYU,MED CTR,DEPT PSYCHIAT NEW YORK NY 10016 COLUMBIA UNIV,COLL PHYS & SURG,DEPT PSYCHIAT NEW YORK NY 00000
Titolo Testata:
Psychopharmacology bulletin
fascicolo: 2, volume: 30, anno: 1994,
pagine: 209 - 213
SICI:
0048-5764(1994)30:2<209:PIAWCD>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBROSPINAL-FLUID MONOAMINE; DISRUPTIVE BEHAVIOR DISORDERS; FAMILY VIOLENCE; ADOLESCENTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
L.E. Sanchez et al., "PLACEBO-RESPONSE IN AGGRESSIVE-CHILDREN WITH CONDUCT DISORDER", Psychopharmacology bulletin, 30(2), 1994, pp. 209-213

Abstract

Aggressiveness and explosiveness characterize a subgroup of children diagnosed with conduct disorder (CD). Few double-blind, placebo-controlled studies have been conducted in aggressive children with CD, and no study has differentiated placebo responders from nonresponders. Thisstudy examined factors that may differentiate placebo responders fromnonresponders hospitalized in a structured setting. The sample consisted of 25 children, ages 6.25 to 11.95 years, with CD and a profile ofaggressive and explosive behavior who were assigned to placebo treatment as part of a double-blind study of lithium. Responders were compared to nonresponders with respect to a detrimental psychosocial environmental score, age, IQ, and baseline ratings on the Children's Psychiatric Rating Scale and Clinical Global Impressions. Responders had significantly higher detrimental psychosocial environmental scores than nonresponders; they were particularly more likely to come from violent homes and to have criminally charged parents. Demographic variables did not distinguish the two groups; however, even mild hyperactivity was associated with poorer response to placebo.

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Documento generato il 08/07/20 alle ore 08:11:59